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Surface membrane enzyme, chemotactic peptide binding activities, and chemotactic responsiveness of rabbit peripheral and peritoneal neutrophils

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Abstract

The chymotrypsin-like esterase activity of plasma membrane and the ecto-5'-nucleotidase and ecto-ρ-nitrophenyl phosphatase activities in peritoneal neutrophils are 2- and 3-fold higher than peripheral blood neutrophils. The binding of the chemotactic peptide, formyl norleucyl-leucyl-phenylalanine to peritoneal neutrophils is 6- to 7-fold higher than to peripheral blood neutrophils. The chemotactic responsiveness of peritoneal neutrophils to the chemotactic peptide is 5-fold greater than peripheral blood neutrophils. However, there was no significant difference in the chemotactic responsiveness to complement component C5a between the blood and peritoneal cells.

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  1. Pi -Kwang Tsung

    Present address: St. Elizabeth's Hospital, 736 Cambridge Street, 02135, Brighton, Massachusetts

Authors and Affiliations

  1. Department of Pathology, University of Connecticut Health Center, 06032, Farmington, Connecticut

    Pi -Kwang Tsung, H. J. Showell & E. L. Becker

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  1. Pi -Kwang Tsung
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  2. H. J. Showell
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  3. E. L. Becker
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Tsung, P.K., Showell, H.J. & Becker, E.L. Surface membrane enzyme, chemotactic peptide binding activities, and chemotactic responsiveness of rabbit peripheral and peritoneal neutrophils. Inflammation 4, 271–277 (1980). https://doi.org/10.1007/BF00915028

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