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Über die Identifizierung von Alkoholen mit 1-Chlormethyl-isatin

The identification of alcohols by means of 1-chloromethyl-isatin

  • Organische Chemie und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

Primary, secondary and tertiary aliphatic alcohols quickly react with 1-chloromethyl-isatin (1) to give good yields of alkoxymethylisatines4-novel derivatives of alcohols with the structure of N,O-acetals; the compounds4 can be prepared also from water containing alcohols. 21 alkoxymethylisatines (4a-4u) were synthesized and tabulated; because of their easy preparation, simple purification and high melting-points they are a useful means for identifying alcohols.

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Literatur

  1. F. Knotz, Scientia pharmac. [Wien]38, 227 (1970).

    Google Scholar 

  2. W. Wendelin undF. Knotz, Mh. Chem.103, 1632 (1972).

    Google Scholar 

  3. Literaturzusammenstellungen über diese Methoden findet man z. B. in:R. L. Shriner, R. C. Fuson, andD. Y. Curtin, The Systematic Identification of Organic Compounds. New York: Wiley. 1964 (mit Tabellen) und in:Stig Veibel, Analytik organischer Verbindungen. Berlin: Akademie-Verlag. 1960.

    Google Scholar 

  4. Fr. Gumpert, J. prakt. Chem. [2]31, 119 (1885).

    Google Scholar 

  5. E. Lambling, Bull. soc. chim. France19, 771 (1898).

    Google Scholar 

  6. T. V. Bickel undH. E. French, J. Amer. Chem. Soc.48, 747 (1926).

    Google Scholar 

  7. C. Neuberg undE. Kansky, Biochem. Z.20, 446 (1909).

    Google Scholar 

  8. H. J. Henstock, J. chem. Soc. [London]1933, 216.

  9. M. D. Armstrong undJ. E. Copenhaver, J. Amer. Chem. Soc.65, 2252 (1943).

    Google Scholar 

  10. T. Reichstein, Helv. Chim. Acta9, 799 (1926).

    Google Scholar 

  11. W. N. Lipscomb undR. H. Baker, J. Amer. Chem. Soc.64, 179 (1942).

    Google Scholar 

  12. B. H. Nicolet undJ. Sacks, J. Amer. Chem. Soc.47, 2348 (1925).

    Google Scholar 

  13. G. M. Dickinson, L. H. Crosson, undJ. E. Copenhaver, J. Amer. Chem. Soc.59, 1094 (1937).

    Google Scholar 

  14. W. A. Feissler undR. L. Shriner, J. Amer. Chem. Soc.58, 1384 (1936).

    Google Scholar 

  15. H. Böhme undH. Schwartz, Arch. Pharmaz.306, 684 (1973).

    Google Scholar 

  16. A. Reissert undA. Händler, Ber. dtsch. chem. Ges.57, 994 (1924).

    Google Scholar 

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Mit 2 Abbildungen

Über die Charakterisierung von Carbonsäuren und von N,H-aciden Verbindungen mit Chlormethylisatin wurde bereits früher berichtet, vgl.1, 2.

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Wendelin, W., Knotz, F. & Schramm, HW. Über die Identifizierung von Alkoholen mit 1-Chlormethyl-isatin. Monatshefte für Chemie 106, 159–168 (1975). https://doi.org/10.1007/BF00914509

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  • DOI: https://doi.org/10.1007/BF00914509

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