Abstract
Primary, secondary and tertiary aliphatic alcohols quickly react with 1-chloromethyl-isatin (1) to give good yields of alkoxymethylisatines4-novel derivatives of alcohols with the structure of N,O-acetals; the compounds4 can be prepared also from water containing alcohols. 21 alkoxymethylisatines (4a-4u) were synthesized and tabulated; because of their easy preparation, simple purification and high melting-points they are a useful means for identifying alcohols.
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Über die Charakterisierung von Carbonsäuren und von N,H-aciden Verbindungen mit Chlormethylisatin wurde bereits früher berichtet, vgl.1, 2.
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Wendelin, W., Knotz, F. & Schramm, HW. Über die Identifizierung von Alkoholen mit 1-Chlormethyl-isatin. Monatshefte für Chemie 106, 159–168 (1975). https://doi.org/10.1007/BF00914509
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DOI: https://doi.org/10.1007/BF00914509