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Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides

Communication 3. Reaction of imidazolide of N-tert-butyloxycarbonylglycine with transfer ribonucleic acids

  • Organic and Biological Chemistry
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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    The optimal conditions of aminoacylation of transfer ribonucleic acids with imidazolide of N-tert-butyloxycarbonylglycine and subsequent removal of the N-protecting group have been determined.

  2. 2.

    The content of different reaction products has been determined and it has been established that at the total yields of aminoacyl derivatives ∼100%, approximately 50% undergo aminoacylation at the acceptor end of tRNA molecules.

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Literature cited

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Authors and Affiliations

  1. Institute of Molecular Biology, Academy of Sciences of the USSR, USSR

    B. P. Gottikh, A. A. Kraevskii, T. L. Tsilevich & L. N. Rudzite

Authors
  1. B. P. Gottikh
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  2. A. A. Kraevskii
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  3. T. L. Tsilevich
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  4. L. N. Rudzite
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 113–121, January, 1970.

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Gottikh, B.P., Kraevskii, A.A., Tsilevich, T.L. et al. Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides. Russ Chem Bull 19, 103–110 (1970). https://doi.org/10.1007/BF00913933

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  • DOI: https://doi.org/10.1007/BF00913933

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