Monatshefte für Chemie / Chemical Monthly

, Volume 108, Issue 3, pp 653–664 | Cite as

Synthese derrac. 1-[3-Hydroxy-1-(E)-octenyl]-2-imidazol-heptansäure

Über die Synthese von prostaglandinanalogen Imidazolen, 1. Mitt.
  • Matthias Pailer
  • Hans Gutwillinger
Organische Chemie und Biochemie

Synthesis of rac. 1-[3-hydroxy-1-(E)-octenyl]-2-imidazoleheptanoic acid


The synthesis of an analogue of natural prostaglandins (I) is described, where the cyclopentane ringsystem is substituted by imidazole.

The pharmacological activity of sodium-salt14 is compared with that of natural prostaglandins.


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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Matthias Pailer
    • 1
  • Hans Gutwillinger
    • 1
  1. 1.Pharmazeutisch-Chemisches InstitutUniversität WienWienÖsterreich

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