Abstract
Derivatives of the following six ring systems were synthesized:
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1.
3,10-Dihydro-[1]benzothieno[2,3-d]imidazo[1,5-a]-pyrimidine (I)
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2.
6H-[1]Benzothieno[2,3-d]pyrazino[1,2-a]pyrimidine (II)
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3.
1,5-Dihydro-[1]benzothieno[2,3-d]imidazo[1,2-a]-pyrimidine (III)
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4.
6H-[1]Benzothieno[2,3-d]pyrimido[1,2-a]pyrimidine (IV)
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5.
1,5-Dihydro-imidazo[1,2-a]thieno[2,3-d]pyrimidine (V)
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6.
4H-Pyrimido[1,2-a]thieno[2,3-d]pyrimidine (VI)
The first four types are new heterocyclic systems. 2-Aminomethyl-5,6,7,8-tetrahydro-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one (5), which was used as intermediate for typesI andII, was synthesized by various methods. TypesIII andIV were prepared from 2-methylthio-5,6,7,8-tetrahydro-[1]-benzothieno[2,3-d]pyrimidin-4(3H)-one via the corresponding 2-benzylamino derivatives, followed by ring closure.
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Literatur
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Sauter, F., Stanetty, P., Schrom, E. et al. Imidazo- und Diazino-Anellierungen an das [1]Benzothieno[2,3—d]pyrimidin-System. Monatshefte für Chemie 109, 53–61 (1978). https://doi.org/10.1007/BF00911944
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DOI: https://doi.org/10.1007/BF00911944