Monatshefte für Chemie / Chemical Monthly

, Volume 110, Issue 2, pp 257–265 | Cite as

Der Einfluß von Stickstoffsubstituenten bei der Synthese von 3-Methyl-1,4-Benzoxazinen

Studien zur Synthese von 1,4-Oxazinen, 2. Mitt.
  • Herbert Bartsch
  • Wolfgang Kropp
  • Matthias Pailer
Organische Chemie und Biochemie

Dependence of nitrogensubstituents in the synthesis of 3-methyl-1,4-benzoxazines


Starting from1 the azomethine2 is obtained. The intermediates4 a and4 b of this reaction sequence cause the high yields. Cyclization of theN-alkylderivatives4 d and8 b leads also to an azomethine, which is obtained as its salt11. Cyclization of theN-acetylderivative13 yields however the anamine14. The structures of the new products are established by chemical and spectroscopic methods.


o-Aminophenoxyacetons, cyclization of 3-Methyl-2H-1,4-benzoxazines 3-Methyl-4H-1,4-benzoxazines 


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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Herbert Bartsch
    • 1
  • Wolfgang Kropp
    • 1
  • Matthias Pailer
    • 1
  1. 1.Institut für Pharmazeutische ChemieUniversität WienWienÖsterreich

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