Conclusions
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1.
A new method of synthesizing 3′- and 2′-O-aminoacylnucleosides and aminoeylnucleotides based on the activation of N-substituted amino acids with imidazole was developed.
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2.
In using this method, it is most convenient to use the o-nitrophenylsulfenyl protection for the amino acid when preparing O-aminoacylnueleosides, and the tert-butyloxycarbonyl group in the case of 5′-nucleotides.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimieheskaya, No. 11, pp. 2571–2573, November, 1967.
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Gottikh, B.P., Kraevskii, A.A., Purygin, P.P. et al. A new method of synthesizing 3′(2′)-O-aminoacylnucleosides and nucleotides. Russ Chem Bull 16, 2453–2455 (1967). https://doi.org/10.1007/BF00911869
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DOI: https://doi.org/10.1007/BF00911869