Catalytic synthesis of nitriles

Communication 5. Conversion of isoalkanols into nitriles by means of ammonia
  • M. A. Popov
  • N. I. Shuikin
Organic and Biological Chemistry


An effective catalyst for the conversion of isoalkanols into nitriles under the action of ammonia is pure zinc oxide at 390°. In presence of zinc oxide at this temperature, isobutyl alcohol reacts with ammonia with formation of isobutyronitrile in yields of up to 76.6% and isopentyl alcohol gives isovaleronitrile under the same conditions in yields of up to 71.4%.


Oxide Alcohol Ammonia Zinc Nitrile 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1962

Authors and Affiliations

  • M. A. Popov
    • 1
  • N. I. Shuikin
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of SciencesUSSR

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