Effect of the sequence of the introduction of foreign substances on the action of papain

  • Krishna Bahadur
  • B. D. Atreya


In general, aniline, aniline hydrochloride, aniline sulfate, and triethylamine act as inhibitors in the hydrolysis of casein or of a suspension of flour from grain of Cicer arietinum by means of papain. The order in which the enzyme and the substrate is added to the inhibitor often has a significant effect. As a rule, there is a greater retardation when the enzyme is added last to a complex of the substrate and the inhibitor.


Enzyme Sulfate Hydrolysis Hydrochloride Aniline 
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Literature cited

  1. 1.
    D.F. Derivchian, Disc. Faraday Soc.6, 7 (1949).Google Scholar
  2. 2.
    E. Chargaff, et al., J. Biol. Chem.139, 383 (1941).Google Scholar
  3. 3.
    J. Klotz, The Proteins (New York, 1953) Vol. 1.Google Scholar
  4. 4.
    F. Putnam, Advances Protein Chem.4, 80 (1948).Google Scholar
  5. 5.
    O.P. Chepinoga, Nucleic Acids and their Biological Significance [in Russian] (Izd. An Ukrain. SSR, Kiev, 1956).Google Scholar
  6. 6.
    D.W. Waugh, Advances Protein Chem.9, 326 (1954).Google Scholar
  7. 7.
    T. Viswanatha, Irvin and E. Liener, J. Biol. Chem.210 (I), 97 (1954).Google Scholar
  8. 8.
    R. Tompsett, S. Schulz, and W. McDermott, J. Bacteriol.53, 581 (1947).Google Scholar
  9. 9.
    B. Davis and R. Dubos, J. Exp. Med.86, 215 (1947).Google Scholar
  10. 10.
    G.A. Deborin, Paper Read at International Symposium on the Origin of Life on the Earth [in Russian] (1957) 1st ed. p. 251.Google Scholar

Copyright information

© Consultants Bureau Enterprises, Inc. 1961

Authors and Affiliations

  • Krishna Bahadur
    • 1
  • B. D. Atreya
    • 1
  1. 1.Chemical Departments of Allahabad University and of the Bhalwant Rajput CollegeIndia

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