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Mass spectrometry of steroid systems

Communication 13. cis-trans-isomerism in the series of estrane and D-homoestrane
  • V. L. Sadovskaya
  • N. S. Vul'fson
  • V. I. Zaretskii
Physical Chemistry

Conclusions

  1. 1.

    The mass spectra of cis- and trans-isomers in the series of estradiol, Δ4-3-ketosteroids, 14-hydroxy derivatives of estrone, and their D-homoanalogs were studied.

     
  2. 2.

    The mass spectra of cis-trans-isomers of polycyclic compounds well reflect the stereochemical peculiarities in the structure of their molecules, which makes it possible to assign the investigated compounds of this type to the trans- or cis-series on the basis of their mass spectra.

     
  3. 3.

    A configuration of the 8- and 14-centers in the molecules of methyl esters of Δ9(11)-dehydro-14β-hydroxy-8-isoestrone, Δ9(11)-dehydro-14α-hydroxy-D-homoestrone, and Δ9(11)-dehydro-14β-hydroxy-8-iso-D-homoestrone, as well as their 9,11-dihydro-derivatives, was proposed.

     

Keywords

Methyl Ester Mass Spectrometry Steroid Mass Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

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Copyright information

© Consultants Bureau 1968

Authors and Affiliations

  • V. L. Sadovskaya
    • 1
  • N. S. Vul'fson
    • 1
  • V. I. Zaretskii
    • 1
  1. 1.Institute of the Chemistry of Natural CompoundsAcademy of Sciences of the USSRUSSR

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