Catalytic synthesis of nitriles
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The optimum conditions were found for the synthesis of benzonitrile, phenylacetonitrile, and hydrocinnamonitrile by reaction of ammonia with benzyl, phenethyl, and 3-phenylpropyl alcohols over a nickelalumina catalyst in a flow system.
In presence of a 3% nickel-alumina catalyst at 390° the yield of benzonitrile attains 51.7%. The maximum yields of phenylacetonitrile (at 300°) and hydrocinnamonitrile (at 330°) are obtained by carrying out the nitrile formation over a 1.5% nickel-alumina catalyst and are 44.8 and 50.8%, respectively.
A hypothesis was advanced on the mechanism of the formation of a small amount of amines and aromatic hydrocarbons as by-products in the nitrile synthesis.
KeywordsAlcohol Ammonia Hydrocarbon Optimum Condition Nitrile
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