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2,4,5-trichlorophenyl esters and their use in synthesis of polypeptides of regular structure

  • Organic and Biological Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    The possiblity of using 2,4, 5-trichlorophenyl esters for synthesis of polypeptides of regular structure has been demonstrated.

  2. 2.

    In their “polymerizing” ability the 2,4, 5-trichlorophenyl esters yield only to pentachlorophenyl esters.

  3. 3.

    Polypeptides of regular structure have been synthesized, with the sequences glycine-prolineglycine, glycine-hydroxyproline-hydroxyproline, and glycine-proline-hydroxyproline; these are models of the collagen structure.

  4. 4.

    The corresponding glycylhydroxyprolylhydroxyproline ester is proposed as a convenient monomer which permits comparing different polymerization methods.

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Literature cited

  1. J. Pless and R. A. Boissonnas, Helv. Chim. Acta,46, 1609 (1963).

    Google Scholar 

  2. G. Kupryszewski and M. Kaczmarek, Roczn. Chem.,35, 939 (1961); G. Kupryszewski and M. Formela, ibid.,35, 1553 (1961).

    Google Scholar 

  3. S. Sakaibara and N. Inuka, Bull. Chem. Soc. Japan,38, 1979 (1965).

    Google Scholar 

  4. J. Pless, Proceedings of the Fifth European Symposium, Oxford (September, 1962), Pergamon Press, Oxford, London-New York-Paris (1963), p. 69.

    Google Scholar 

  5. V. A. Shibnev, A. V. Lisovenko, T. P. Chuvaeva, and K. T. Poroshin, Izv. Akad. Nauk SSSR, Ser. Khim., 2564 (1968).

  6. V. A. Shibnev, A. V. Lisovenko, T. P. Chuvaeva, V. S. Grechishko, and K. T. Poroshin, Dokl. Akad. Nauk Tadzh. SSSR,9, 16 (1966).

    Google Scholar 

  7. V. A. Shibnev, T. P. Chuvaeva, and K. T. Poroshin, Izv. Akad. Nauk SSSR, Ser. Khim., 225 (1968).

  8. N. S. Andreeva, N. G. Esipova, M. I. Millionova, V. A. Rogulenkova, and V. A. Shibnev, Molekulyarnaya Biologiya,1, 5, 657 (1967).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Molecular Biology of the Academy of Sciences of the USSR, USSR

    V. A. Shibnev, T. P. Chuvaeva, G. A. Martynova & K. T. Poroshin

  2. V. I. Lenin Tadjik State University, USSR

    V. A. Shibnev, T. P. Chuvaeva, G. A. Martynova & K. T. Poroshin

Authors
  1. V. A. Shibnev
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  2. T. P. Chuvaeva
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  3. G. A. Martynova
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  4. K. T. Poroshin
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 637–643, March, 1969.

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Shibnev, V.A., Chuvaeva, T.P., Martynova, G.A. et al. 2,4,5-trichlorophenyl esters and their use in synthesis of polypeptides of regular structure. Russ Chem Bull 18, 570–575 (1969). https://doi.org/10.1007/BF00906979

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  • DOI: https://doi.org/10.1007/BF00906979

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