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Monatshefte für Chemie / Chemical Monthly

, Volume 107, Issue 2, pp 405–409 | Cite as

Stereochemie vonGrignard-Reaktione mit 2-(N-Methylanikino)-cyclopentanonen

  • Hans Berbalk
  • Karl Eichinger
  • Eleonore Decker
Organische Chemie und Biochemie

Stereochemistry of Grignard-reactions with 2-(N-methylanilino)-cyclopentanones

Abstract

TheGrignard reactions of the 2-anilinocyclopentanones (1 a and1 b) with CH3MgI and C6H5C≡CMgBr, giving the 2-anilinocyclopentanols2 a, 2 b, and2 c, and the synthesis oftrans-1-methyl-2-(4-chloro-N-methylanilino)-cyclopentanol (4), which was used as a reference compound of known stereochemistry, are described. IR spectroscopic investigations of2 a, 2 b, and2 c as compared with4 lead to the conclusion that2 a, 2 b, and2 c have the structures ofcis-2-(N-methylanilino)-cyclopentanols.

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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • Hans Berbalk
    • 1
  • Karl Eichinger
    • 1
  • Eleonore Decker
    • 1
  1. 1.Abteilung für Analytische Chemie, Institut für Organische ChemieTechnische Universität WienWienÖsterreich

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