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Mass spectrometric investigations of organic compounds

Communication 1. Quantitative analysis of a mixture of steroids
  • A. M. Zyakun
  • V. É. Sterkin
  • G. R. Morozova
  • V. M. Adanin
Inorganic and Analytical Chemistry

Conclusions

  1. 1.

    The possibility of a quantitative mass spectrometric determination of prednisolone and hydrocortisone present in a mixture was demonstrated.

     
  2. 2.

    The use of the MI-1305 mass spectrometer permits the analysis of a mixture of two steroid preparations within 30 min, with an amount of sample required of 0.01 μmole.

     

Keywords

Steroid Hydrocortisone Mass Spectrometer Organic Compound Prednisolone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    A.A Akhrem and Yu.A. Titov, Microbiological Transformations of Steroids [in Russian], Nauka (1965).Google Scholar
  2. 2.
    G.K. Skryabin and L.M. Kogan, Izv. AN SSSR, Ser. Biol., No. 5, 742 (1967).Google Scholar
  3. 3.
    I.M Hais and K. Macek, Paper Chromatography [Russian translation], IL (1962).Google Scholar
  4. 4.
    J. Beinon, Mass Spectrometry and Its Use in Organic Chemistry [Russian translation], Mir (1964), p. 439.Google Scholar
  5. 5.
    A. M. Zyakun, “A thermostatically controlled system of evaporating the sample for the MKh-1303 mass spectrometer,” Pribory i Tekhnika Éksperimenta, No. 4, 162 (1967).Google Scholar

Copyright information

© Consultants Bureau 1969

Authors and Affiliations

  • A. M. Zyakun
    • 1
  • V. É. Sterkin
    • 1
  • G. R. Morozova
    • 1
  • V. M. Adanin
    • 1
  1. 1.Institute of the Biochemistry and Physiology of MicroorganismsAcademy of Sciences of the USSRUSSR

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