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Monatshefte für Chemie / Chemical Monthly

, Volume 107, Issue 5, pp 1193–1197 | Cite as

Synthesen von 5-Alkyl-2-aryl-pyrimidin-4(3H)-onen

  • Fritz Sauter
  • Peter Stanetty
  • Ferdinand Fuhrmann
Organische Chemie und Biochemie

Syntheses of 5-alkyl-2-aryl-pyrimidin-4(3H)-ones

Abstract

The title substances with R2=H (type1) were synthesized by reductive desulfurization of corresponding 2-aryl-thieno-[2,3-d]pyrimidin-3(3H)-ones and 2-aryl-[1]benzothieno[2,3-d]-pyrimidin-4(3H)-ones (both:A), those with R2=CH3 (type2) by cyclization of α-alkyl-acetoacetates with benzamidines. Some derivatives of1 and2 were also prepared (type3). In some cases Raney-Ni desulfurization ofA gave 2-cyclohexylproducts (type4).

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Literatur

  1. 1.
    H. W. van Meeteren undH. C. van der Plas, Rec. Trav. Chim.1968, 1089.Google Scholar
  2. 2.
    H. J. Minnemeyer, J. Org. Chem.31, 406 (1966).Google Scholar
  3. 3.
    A. Pinner, Ber. dtsch. chem. Ges.22, 1612 (1889);23 3826 (1890);28, 485 (1895).Google Scholar
  4. 4.
    K. E. Schulte, J. Reisch, A. Mock undK. H. Kauder, Arch. Pharm.296, 235 (1963).Google Scholar
  5. 5.
    F. Sauter, P. Stanetty, H. Potužak undM. Baradar, Mh. Chem.107, 669 (1976).Google Scholar
  6. 6.
    F. Fuhrmann, Diplomarbeit, Technische Universität Wien, 1975.Google Scholar
  7. 7.
    M. Baradar, Diplomarbeit, Technische Hochschule Wien, 1973.Google Scholar

Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • Fritz Sauter
    • 1
  • Peter Stanetty
    • 1
  • Ferdinand Fuhrmann
    • 1
  1. 1.Institut für Organische ChemieTechnische Universität WienWienÖsterreich

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