Monatshefte für Chemie / Chemical Monthly

, Volume 107, Issue 5, pp 1193–1197 | Cite as

Synthesen von 5-Alkyl-2-aryl-pyrimidin-4(3H)-onen

  • Fritz Sauter
  • Peter Stanetty
  • Ferdinand Fuhrmann
Organische Chemie und Biochemie

Syntheses of 5-alkyl-2-aryl-pyrimidin-4(3H)-ones


The title substances with R2=H (type1) were synthesized by reductive desulfurization of corresponding 2-aryl-thieno-[2,3-d]pyrimidin-3(3H)-ones and 2-aryl-[1]benzothieno[2,3-d]-pyrimidin-4(3H)-ones (both:A), those with R2=CH3 (type2) by cyclization of α-alkyl-acetoacetates with benzamidines. Some derivatives of1 and2 were also prepared (type3). In some cases Raney-Ni desulfurization ofA gave 2-cyclohexylproducts (type4).


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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • Fritz Sauter
    • 1
  • Peter Stanetty
    • 1
  • Ferdinand Fuhrmann
    • 1
  1. 1.Institut für Organische ChemieTechnische Universität WienWienÖsterreich

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