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Über 4-Ureidooctahydropyrano[4,3-d]pyrimidinone

Heterocycles, XVIII: 4-Ureido-octahydropyrano[4,3-d]-pyrimidinones

Über Heterocyclen, 18. Mitt.

  • Organische Chemie und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Zusammenfassung

5,6-Dihydro-2H-pyran-3-aldehyde reagieren mit Harnstoff zu 4-ureidooctahydropyrano[4,3-d]pyrimidin-2-ones. Einwirkung von Säure führt das 4-Ureidooctahydropyrano[4,3-d]pyrimidin-2-on in das 4-(2-Hydroxyäthyl)-hexahydropyrimido[4,5-d]pyrimidin-2,7-dion über.

Abstract

5,6-Dihydro-2H-pyran-3-aldehydes react with urea to give 4-ureidooctahydropyrano[4,3-d]pyrimidin-2-ones. 4-Ureidooctahydropyrano[4,3-d]pyrimidin-2-one is cleaved by HCl to 4-(2-hydroxyethyl)-hexahydropyrimido[4,5-d]pyrimidin-2,7-dione.

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Authors and Affiliations

  1. Institut für Pharmazeutische Chemie der Universität Graz, Graz, Österreich

    G. Zigeuner, E. A. Gardziella & W. Wendelin

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  1. G. Zigeuner
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  2. E. A. Gardziella
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  3. W. Wendelin
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Zigeuner, G., Gardziella, E.A. & Wendelin, W. Über 4-Ureidooctahydropyrano[4,3-d]pyrimidinone. Monatshefte für Chemie 100, 1140–1145 (1969). https://doi.org/10.1007/BF00903446

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  • DOI: https://doi.org/10.1007/BF00903446

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