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Zeitschrift für Vererbungslehre

, Volume 97, Issue 1, pp 1–9 | Cite as

Mutationsorte vom oo-Typ in einem Strukturgen

  • U. Henning
  • G. Dennert
  • K. Szolyvay
  • G. Deppe
Article

Summary

In two oo-type mutant strains ofE. coli K12 the mutant sites are shown to be located entirely within the structural gene of the decarboxylase component of the pyruvate dehydrogenase complex. One of the two mutant sites (probably of theochre-type) could be converted by mutation to anamber site which also completely inhibits the expression of the closely linked structural genes. The inhibition, therefore, is apparently caused by an inability to initiate, or an early termination of, the synthesis of the decarboxylase protein.

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Copyright information

© Springer-Verlag 1965

Authors and Affiliations

  • U. Henning
    • 1
  • G. Dennert
    • 1
  • K. Szolyvay
    • 1
  • G. Deppe
    • 1
  1. 1.Institut für Genetik der Universität zu Köln5 Köln-Lindenthal

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