Zeitschrift für Vererbungslehre

, Volume 94, Issue 4, pp 331–335 | Cite as

The effect of cyanide and azide on the mutagenic activity of the pyrrolizidine alkaloid heliotrine inDrosophila melanogaster

  • N. G. Brink


Neither cyanide nor azide were found to increase the spontaneous sex-linked lethal frequency or the chromosome breakage frequency inDrosophila. However, both inhibitors produced a slight increase in the heliotrine induced sex-linked lethal and chromosome breakage frequencies in all broods except for the possible exception of the first, the increase for the combined brood totals being statistically significant. Possible mechanisms underlying the enhancing effects of both cyanide and azide are discussed.


Cyanide Alkaloid Azide Enhance Effect Mutagenic Activity 
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Copyright information

© Springer-Verlag 1963

Authors and Affiliations

  • N. G. Brink
    • 1
  1. 1.Department of ZoologyUniversity of TasmaniaTasmania(Australien)

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