Zeitschrift für Vererbungslehre

, Volume 98, Issue 4, pp 375–384 | Cite as

Super-suppressor induced interallelic complementation

  • S. G. Inge-Vechtomov
  • B. V. Simarov
  • T. R. Soidla
  • S. A. Kožin


In yeast the dominant super-suppressorS5 has a distinct expression in heterozygotes depending on the particular combination of alleles at thead1 orad2 loci. If thead1 combination is represented by two suppressible alleles, the phenotype of diploid is wild. If thead1 combination consists of a suppressible and a non-suppressible allele the phenotype of the diploid is partially mutant. Such a difference in the manifestation of suppressor depending on the combination of alleles is more pronounced in the case ofad2 mutations. In the case when bothad2 alleles are suppressible, the diploid is prototrophic, but when only one allele is suppressible, the diploid is an adenineless auxotroph as a rule.

This type ofS5-effect gave us the possibility to study interallelic complementation atad2 locus in presence of the super-suppressor. It was shown that some combinations of noncomplementing alleles do complement as a result of suppression.

Comparison of the two complementation maps with and without suppressor is made for thead2 locus. The mechanisms of the phenomena and of super-suppression are discussed.


Suppressible Allele Interallelic Complementation 
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Copyright information

© Springer-Verlag 1966

Authors and Affiliations

  • S. G. Inge-Vechtomov
    • 1
  • B. V. Simarov
    • 1
  • T. R. Soidla
    • 1
  • S. A. Kožin
    • 1
  1. 1.Department of GeneticsLeningrad UniversityLeningradUSSR

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