Summary
The sensitivity of the capacity for forming galactokinase inE. coli was measured under various conditions. Differences were found between strains W 8 and Hfr 7 (λ) and between these strains and mutants, derived from them, which are partially constitutive for galactokinase. The same behavior as that of the constitutive mutants was also obtained for Hfr 7 (λ) induction of the genes for galactokinase or β-galactosidase prior to UV-irradiation. It was concluded that these genes exhibit different sensitivities toward UV, depending on whether they are in the repressed or de-repressed state. Pre-induction effects on UV-sensitivity are observed only in strain Hfr 7 (λ) and only if the latter is lysogenic for phage λ.
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Kölsch, E., Starlinger, P. A difference in UV-sensitivity between genes in the repressed and genes in the de-repressed state. Zeitschrift für Vererbungslehre 96, 297–303 (1965). https://doi.org/10.1007/BF00895045
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DOI: https://doi.org/10.1007/BF00895045