Zeitschrift für Vererbungslehre

, Volume 95, Issue 2, pp 184–194 | Cite as

Effects of radioactive decay on the autonomous replicatin of anEscherichia coli episome

  • Yukinori Hirota
  • Hisao Uchida


TheE. coli episomeF13 loses its capacity for autonomous replication when the integrity of the molecule is impaired by the decay of32P atoms incorporated into its polynucleotide chains. Upon further division of the host bacteria, the distal fragments near the episomal terminus are eliminated, whereas, the proximal fragments near the episomal origin may survive as heterogenotes attached to the host chromosome.


Radioactive Decay Polynucleotide Distal Fragment Host Bacterium Proximal Fragment 
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Copyright information

© Springer-Verlag 1964

Authors and Affiliations

  • Yukinori Hirota
    • 1
  • Hisao Uchida
    • 1
  1. 1.The Institute for Infectious DiseasesThe University of TokyoTokyoJapan

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