Weitere Untersuchungen zu Komplementarität und Nicht-Autonomie Deraugenfarb-MutantenMA-L undMA-L ^BZ vonDrosophila melanogaster

Summary

Data found byGlassman (1959, 1960) in compound females of the genotypev bz/v f B x ma-l (wherebz stands forma-l ^bz) showed complementation between these “alleles” in both eye color and activity of the enzyme, xanthine dehydrogenase, the latter however being incomplete. These results have been reexamined and extended, using compounds of purebz andma-l stocks as well as various heterozygotes between these stocks and the mutantrosy. Complementation in the red eye pigments (drosopterines), though incomplete in newly emerged compound femalesma-l/bz andbz/ma-l becomes firmly established in older flies, where the red pigments reach the amount present in wildtype eyes. Isoxanthopterin however, as well as enzyme activity do not exceed approximately 10% of the level typical for wildtype. These features of slow and incomplete complementation are very probably due to the interaction ofma-l andbz; they do not occur in a series of other related heterozygotes.

Transplantation experiments revealed non-autonomy of bothma-l andbz with regard to the formation of drosopterines in the eyes and isoxanthopterin in the testes.

The results are discussed with respect to the allelsm of the two mutants.