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Effects of chloramphenicol and of multiplicity of infection on induced mutation in bacteriophage T4

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Bibliography

  • Benzer, S.: Fine structure of a genetic region in bacteriophage. Proc. nat. Acad. Sci. (Wash.)41, 344 (1955).

    Google Scholar 

  • —: On the topology of the genetic fine structure. Proc. nat. Acad. Sci. (Wash.)45, 1607 (1959).

    Google Scholar 

  • Brenner, S., andJ. D. Smith: Induction of mutations in the deoxyribonucleic acid of phage T2 synthesized in the presence of chloramphenicol. Virology8, 124 (1955).

    Google Scholar 

  • Burton, K.: The relation between the synthesis of deoxyribonucleic acid and the synthesis of protein in the multiplication of bacteriophage T2. Biochem. J.61, 473 (1955).

    PubMed  Google Scholar 

  • Ellis, E., andM. Delbrück: The growth of bacteriophage. J. gen. Physiol.22, 365 (1939).

    Google Scholar 

  • Fermi, G., andG. S. Stent: Protein synthesis and the onset of intracellular bacteriophage growth. III. Replication of the genome of a secondary phage. J. mol. Biol.4, March (1962).

  • Freese, E.: On the molecular explanation of spontaneous and induced mutations. Brookhaven Symp. Biol.12, 63 (1959).

    Google Scholar 

  • Hershey, A. D., J. Dixon andM. Chase: Nucleic acid economy in bacteria infected with bacteriophage T2: I. Purine and pyrimidine composition. J. gen. Physiol.36, 777 (1953).

    PubMed  Google Scholar 

  • —, andN. E. Melechen: Synthesis of phage-precursor nucleic acid in the presence of chloramphenicol. Virology3, 207 (1957).

    PubMed  Google Scholar 

  • Litman, R. M., andA. B. Pardee: Production of bacteriophage mutants by a disturbance of deoxyribonucleic acid synthesis. Nature (Lond.)178, 529 (1956).

    Google Scholar 

  • Litman, R. M., andA. B. Pardee: Mutations of bacteriophage T2 induced by bromouracil in the presence of chloramphenicol. Virology8 (1959).

  • ——: The induction of mutants of bacteriophage T2 by 5-bromouracil. III. Nutritional and structural evidence regarding mutagenic action. Biochim. biophys. Acta42, 117 (1960).

    PubMed  Google Scholar 

  • McFall, E., andG. S. Stent: Three star mutants of coliphage T2. J. gen. Microbiol.18, 346 (1958).

    PubMed  Google Scholar 

  • Pratt, D., andG. S. Stent: Mutational heterozygotes in bacteriophages. Proc. nat. Acad. Sci. (Wash.)45, 1507 (1959).

    Google Scholar 

  • —— andP. D. Harriman: Stabilization to32P decay and onset of DNA replication of T4 bacteriophage. J. mol. Biol.3, 409 (1961).

    PubMed  Google Scholar 

  • Streisinger, G.: The genetic control of host range and serological specificity in bacteriophages T2 and T4. Virology2, 377 (1956).

    PubMed  Google Scholar 

  • —, andN. Franklin: Mutation and genetic recombination at the host range genetic region of phage T2. Cold Spr. Harb. Symp. quant. Biol.21, 103 (1956).

    Google Scholar 

  • Sussman, M., andR. S. Edgar: Personal communication (1961).

  • Tomizawa, J.: Sensitivity of phage precursor nucleic acid, synthesized in the presence of chloramphenicol, to ultraviolet irraditation. Virology6, 55 (1958).

    PubMed  Google Scholar 

  • —, andS. Sunakawa: The effects of chloramphenicol on deoxyribonucleic acid synthesis and the development of resistance to ultraviolet irradiation inE. coli infected with bacteriophage T2. J. gen. Physiol.39, 553 (1956).

    PubMed  Google Scholar 

  • Vidaver, G. A., andL. M. Kozloff: The rate of synthesis of deoxyribonucleic acid inEscherichia coli B infected with T2r + bacteriophage. J. biol. Chem.225, 335 (1957).

    PubMed  Google Scholar 

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Author notes

  1. Giulio Fermi

    Present address: Abteilung Reichardt, Max-Planck-Institut für Biologie, Tübingen, Calif., Germany

Authors and Affiliations

  1. Virus Laboratory, University of California, Berkeley, Calif., USA

    Giulio Fermi & Gunther S. Stent

Authors
  1. Giulio Fermi
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  2. Gunther S. Stent
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Fermi, G., Stent, G.S. Effects of chloramphenicol and of multiplicity of infection on induced mutation in bacteriophage T4. Zeitschrift für Vererbungslehre 93, 177–187 (1962). https://doi.org/10.1007/BF00889160

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  • DOI: https://doi.org/10.1007/BF00889160

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