Skip to main content
SpringerLink
Log in

Mitotic recombination induced inSaccharomyces cerevisiae with nitrous acid, diethylsulfate and carcinogenic, alkylating nitrosamides

  • Published:
Zeitschrift für Vererbungslehre Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Abadessa, R., andA. B. Burdick: The effect of X-irradiation on somatic crossing over inDrosophila melanogaster. Genetics48, 1345–1356 (1963).

    PubMed  Google Scholar 

  • Bauer, K. H.: Das Krebsproblem, 2. Aufl. Berlin-Göttingen-Heidelberg: Springer 1963.

    Google Scholar 

  • Becker, H. J.: Über Röntgenmosaikflecken und Defektmutationn am Auge vonDrosophila und die Entwicklungsphysiologie des Auges. Z. indukt. Abstamm.-u. Vererb.-Lehre88, 333–373 (1966).

    Google Scholar 

  • Carbondale Yeast Genetics Conference. Microbiol. Genet. Bull.19 Suppl. 1–21 (1963).

  • Druckery, H., andR. Preussmann: N-nitroso-N-methylurethane: A potent carcinogen. Nature (Lond.)195, 1111 (1962).

    Google Scholar 

  • ——,S. Ivancovic, B. T. So, C. H. Schmidt u.J. Bücheler: Zur Erzeugung subcutaner Sarkome an Ratten. Carcinogene Wirkung von Hydrazo-dicarbonsäure-bis-(methylnitrosamid), N-Nitroso-N-n-butyl-harnstoff, N-methyl-N-nitroso-nitroguanidin und N-Nitrosoimidazolidon. Z. Krebsforsch.68, 87–102 (1966).

    PubMed  Google Scholar 

  • Esposito, R. E., andR. Holliday: The effect of 5-flurodeoxyuridine on genetic replication and mitotic crossing over in synchronized cultures ofUstilago maydis. Genetics50, 1009–1017 (1964).

    PubMed  Google Scholar 

  • Fogel, S., andD. D. Hurst: Coincidence relations between gene conversion and mitotic recombination inSaccharomyces. Genetics48, 321–328 (1963).

    PubMed  Google Scholar 

  • Haefner, K.: Zum Mechanismus der Entstehung auxotropher Zellen in heterozygotenSaccharomyces-Stämmen nach UV- und Röntgen-Bestrahlung. Z. Vererbungsl.98, 82–90 (1966).

    PubMed  Google Scholar 

  • Holliday, R.: Induced mitotic crossing-over inUstilago maydis. Genet. Res.2, 231–248 (1961).

    Google Scholar 

  • —: The induction of mitotic recombination by mitomycin C inUstilago andSaccharomyces. Genetics50, 323–335 (1964).

    PubMed  Google Scholar 

  • —: A mechanism for gene conversion in fungi. Genet. Res.5, 282–304 (1964).

    Google Scholar 

  • —: Induced mitotic crossing-over in relation to genetic replication in synchronously dividing cells ofUstilago maydis. Genet. Res.6, 104–120 (1965).

    Google Scholar 

  • Hurst, D. D., andS. Fogel: Mitotic recombination and heteroallelic repair inSaccharomyces cerevisiae. Genetics50, 435–458 (1964).

    PubMed  Google Scholar 

  • James, A. P., andB. Lee-Whiting: Rediation induced genetic segregations in vegetative cells of yeast. Genetics40, 826–831 (1955).

    Google Scholar 

  • Johnston, J. R., andJ. M. Mackinnon: Spontaneous and induced mitotic recombination in diploid and tetraploidSaccharomyces. Abstract, 2nd Internat. Sympos. on Yeasts, Bratislava 1966.

  • Lochmann, E. R., u.W. Stein: Die Wirkung von Natriumnitrit auf Nucleinsäurebasen und ihr Verhältnis zur Inaktivierung von Hefezellen. Z. Naturforsch.18b, 809–816 (1963).

    Google Scholar 

  • Loprieno, N., andC. H. Clarke: Investigations on reversions to methionine independence induced by mutagens inSchizosaccharomyces pombe. Mutation Res.2, 312–319 (1965).

    PubMed  Google Scholar 

  • —,G. Zetterberg, R. Guglielminetti, andE. Michel: The lethal and mutagenic effects of N-nitroso-N-methyl-urethane and N-nitroso-N-ethylurethane inColletotrichum coccodes. Mutation Res.1, 37–44 (1964).

    Google Scholar 

  • Mandell, J. D., andJ. Greenberg: A new chemical mutagen for bacteria, 1-methyl-3-nitro-1-nitrosoguanidine. Biochem. biophys. Res. Commun.3, 575–577 (1960).

    PubMed  Google Scholar 

  • Marquardt, H.: Über Bau, Häufigkeit und Auswirkung der spontanen Translokationen. Flora (Jena)35, 239–302 (1941).

    Google Scholar 

  • —: The mutation hypothesis of chemically induced cancer: Results of recent experiments. Germ. med. Mth.3, 107–114 (1965).

    Google Scholar 

  • —,F. K. Zimmermann u.R. Schwaier: Nitrosamide als mutagene Agentien. Naturwissenschaften50, 625 (1963).

    Google Scholar 

  • ———: Die Wirkung krebsauslösender Nitrosamine und Nitrosamide auf das Adenin-6-45-Rückmutationssystem vonSaccharomyces cerevisiae. Z. Vererbungsl.95, 82–96 (1964).

    PubMed  Google Scholar 

  • Megnet, R.: Screening of auxotrophic mutants of Schizosaccharomyces pombe with 2-deoxyglucose. Mutation Res.2, 328–331 (1965).

    PubMed  Google Scholar 

  • Miller, J. J.: A comparision of the effects of several nutrients and inhibitors on yeast meiosis and mitosis. Exp. Cell Res.33, 46–49 (1964).

    PubMed  Google Scholar 

  • Morpurgo, G.: Induction of mitotic crossing-over inAspergillus nidulans by bifunctional alkylating agents. Genetics48, 1159–1263 (1963).

    Google Scholar 

  • Mortimer, R. K.: X-ray-induced homozygosis in diploid yeast. (Abstr.) Radiat. Res.7, 439–440 (1957).

    Google Scholar 

  • Nakai, S.: Experiments reported byR. C. von Borstel. Yeast Genetics: Science152, 1287–1288 (1966).

    Google Scholar 

  • Nashed, N., andG. Jabbur: A genetic and functional characterization of adenine mutants induced in yeast by 1-nitroso-imidazolidone-2 and nitrous acid. Z. Vererbungsl.98, 106–110 (1966).

    PubMed  Google Scholar 

  • Parry, J. M., andB. S. Cox: Photoreactivation of mititic recombination in yeast. (Abstr.) 2nd Internat. Sympos. on Yeasts, Bratislava (1966).

  • ——: Photoreactivation of ultraviolet induced reciprocal recombination, gene conversion and mutation to prototrophy inSaccharomyces cerevisiae. J. gen. Microbiol.402, 235–241 (1965).

    Google Scholar 

  • Pontecorvo, G., andE. Käfer: Genetic analysis based on mitotic recombination. Advanc. Genet.9, 71–104 (1958).

    Google Scholar 

  • —,J. A. Roper, L. M. Hemmons, K. D. MacDonald, andA. W. J. Bufton: The Genetics ofAspergillus nidulans. Advanc. Genet.5, 141–238 (1953).

    Google Scholar 

  • Roman, H., andF. Jacob: A comparison of spontaneous and ultraviolet-induced allelic recombination with reference to the recombination of outside markers. Cold Spr. Harb. Symp. quant. Biol.23, 155–160 (1958).

    Google Scholar 

  • Schuster, H.: Die Reaktionsweise der Desoxyribonukleinsäure mit salpetriger Säure. Z. Naturforsch.15b, 298–304 (1960).

    Google Scholar 

  • Schwaier, R.: Vergleichende Mutationsversuche mit sieben Nitrosamiden im Rückmutations-test an Hefen. Z. Vererbungsl.97, 55–67 (1965).

    Google Scholar 

  • Sherman, F., andH. Roman: Evidence for two types of allelic recombination in yeast. Genetics48, 255–261 (1963).

    PubMed  Google Scholar 

  • Stern, C.: Somatic crossing over and segregation inDrosophila melanogaster. Genetics21, 625–730 (1936).

    Google Scholar 

  • Swan, P. S., V. M. Craddock, andP. M. Magee: Quantitative comparison of methylation of nucleic acids in rats treated with N-nitroso-methyl-urea and dimethylsulfate. 2nd Meeting Federat. Europ. Biochem. Soc. (Abstr.) 1965, p. 322.

  • Wilkie, D., andB. K. Lee: Genetic analysis of actidione resistance in Saccharomyces cerevisiae. Genet. Res.6, 130–138 (1965).

    Google Scholar 

  • —, andD. Lewis: The effect of ultraviolet light on recombination in yeast. Genetics48, 1701–1716 (1963).

    PubMed  Google Scholar 

  • Woods, R. A., andE. A. Bevan: Interallelic complementation at the ad-2 locus ofSaccharomyces cerevisiae. Heredity21, 121–130 (1966).

    PubMed  Google Scholar 

  • Zetterberg, G.: A specific strong mutagenic effect of N-nitroso-N-methylurethan inOphiostoma. Hereditas (Lund)47, 295–303 (1961).

    Google Scholar 

  • Zimmermann, F. K., R. Schwaier, andU. v.Laer: The influence of pH on the mutagenicity in yeast of N-methylnitrosamides and nitrous acid. Z. Vererbungsl.97, 68–71 (1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Forstbotanisches Institut der Universität Freiburg i. Br., 78, Freiburg i. Br., (Germany)

    F. K. Zimmermann, R. Schwaier & U. v. Laer

Authors
  1. F. K. Zimmermann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Schwaier
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. U. v. Laer
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

We wish to dedicate this publication to Dr.J. G. Zimmermann on occasion of his 60th birthday.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zimmermann, F.K., Schwaier, R. & v. Laer, U. Mitotic recombination induced inSaccharomyces cerevisiae with nitrous acid, diethylsulfate and carcinogenic, alkylating nitrosamides. Zeitschrift für Vererbungslehre 98, 230–246 (1966). https://doi.org/10.1007/BF00888949

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00888949

Keywords

Search

Navigation