Enhancement of antitumor immunity by thymosin in hypocorticalism
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Bilateral adrenalectomy and administration of thymosin (fraction 3) after adrenalectomy inhibit to different degrees the development of mammary gland tumors induced in rats by 7,12-dimethylbenzanthracene. The maximal effect was observed from the use of thymosin in conjunction with hypocorticalism; there was a substantial reduction in the frequency of developing neoplasms, the latent period of their development was lengthened, and their growth retarded.
Key Wordsinduced tumor thymosin adrenalectomy
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- 2.E. D. Chirvina, R. R. Smiller, and A. M. Tyutyunova, Vopr. Onkol., No. 1, 15 (1971).Google Scholar
- 4.J. J. Costanzi, R. G. Gagliano, F. Delaney, et al., Cancer (Philadelphia),40, 14 (1977).Google Scholar
- 8.A. Schreck, Am. J. Cancer,24, 807 (1935).Google Scholar
- 9.M. Small and N. Trainin, J. Exp. Med.,134, 786 (1971).Google Scholar
- 10.G. Turowski, L. Cybulski, M. Politowski, et al., Bull. Soc. Int. Chir.,34, 292 (1975).Google Scholar