Bulletin of Experimental Biology and Medicine

, Volume 88, Issue 2, pp 892–894 | Cite as

Enhancement of antitumor immunity by thymosin in hypocorticalism

  • Yu. A. Grinevich
  • L. Ya. Kamenets
  • V. F. Chebotarev
  • T. N. Selezneva
Oncology

Abstract

Bilateral adrenalectomy and administration of thymosin (fraction 3) after adrenalectomy inhibit to different degrees the development of mammary gland tumors induced in rats by 7,12-dimethylbenzanthracene. The maximal effect was observed from the use of thymosin in conjunction with hypocorticalism; there was a substantial reduction in the frequency of developing neoplasms, the latent period of their development was lengthened, and their growth retarded.

Key Words

induced tumor thymosin adrenalectomy 

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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Yu. A. Grinevich
  • L. Ya. Kamenets
  • V. F. Chebotarev
  • T. N. Selezneva

There are no affiliations available

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