Pediatric Nephrology

, Volume 9, Issue 6, pp 734–736 | Cite as

Pubertal growth in children with chronic renal failure on conservative treatment

  • Cesare Polito
  • Angela La Manna
  • Antonio Iovene
  • Donatella Stabile
Original Article

Abstract

The pubertal growth spurt was followed for at least 3 years in 5 boys and 6 girls with chronic renal failure on conservative treatment. The peak height velocity averaged 8.6 cm/year (range 5.8–10.1 cm/year) in males and 8.2 cm/year (range 6.4–11.5 cm/year) in females. In none was the pubertal growth spurt below the 3rd percentile for chronological age. At the end of the follow-up period, all patients but 2 had stature within the normal limits of parental target. The relative variation of height averaged —0.013 standard deviation scores per year. On the whole, the pubertal growth spurt was normal in subjects with chronic renal failure on conservative treatment.

Key words

Chronic renal failure Pubertal growth spurt Stature 

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References

  1. 1.
    Schaefer F, Seidal C, Binding A, Gasser T, Largo RH, Prader A, Scharer K (1990) Pubertal growth in chronic renal failure. Pediatr Res 28:5–10Google Scholar
  2. 2.
    Kleinknecht C, Broyer M, Huot D, Marti-Hennerberg C, Dartois A (1983) Growth and development of nondialyzed children with chronic renal failure. Kidney Int 24:40–46Google Scholar
  3. 3.
    Rizzoni G, Basso T, Setari M (1984) Growth in children with chronic renal failure on conservative treatment. Kidney Int 26: 52–58Google Scholar
  4. 4.
    Schaefer F, Scharer K, Mehls O (1991) Pathogenic mechanisms of pubertal growth failure in chronic renal failure. Acta Paediatr Scand 379:3–10Google Scholar
  5. 5.
    Van Renen MJ, Hogg RJ, Sweeney AL, Henning PH, Penfold JL, Jureidini KF (1992) Accelerated growth in short children with chronic renal failure treated with both strict dietary therapy and recombinant growth hormone. Pediatr Nephrol 6:451–458Google Scholar
  6. 6.
    Schwartz GJ, Brion LP, Spitzer A (1987) The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children and adolescents. Pediatr Clin North Am 34: 571–590Google Scholar
  7. 7.
    Polito C, Strano CG, Rea L, Alessio M, Iammarrone CS, Todisco N, Marotta A, Laccarino E, Pirozzi M (1995) Reduced bone mineral content and normal serum osteocalcin in non steroid treated JRA patients. Ann Rheum Dis 54:193–196Google Scholar
  8. 8.
    Tanner JM (1978) Foetus into man: physical growth from conception to maturity. Open Books, LondonGoogle Scholar
  9. 9.
    Tanner JM, Whitehouse RH (1976) Ciinical longitudinal standards for height, weight, height velocity, weight velocity and stage of puberty. Arch Dis Child 51:170–179Google Scholar
  10. 10.
    Greco L, Mayer M, Grimaldi M, Capasso G (1982) Factors affecting growth in Campania's schoolchildren. Acta Med Auxol 14: 177–187Google Scholar
  11. 11.
    Tanner JM, Whitehouse RH, Cameron N, Marshall WA, Healey MHR, Goldstein H (1983) Assessment of skeletal maturity and prediction of adult height (TW2 method). Academic Press, LondonGoogle Scholar
  12. 12.
    Saggese G, Federico G, Ghizzi P, Cipriani J, Bertelloni S, Igli Baroncelli G (1986) Densitometria ossea in età pediatrica. Valori normali fra 2 e 19 anni. Primi dati italiani. Minerva Pediatr 38: 545–551Google Scholar

Copyright information

© IPNA 1995

Authors and Affiliations

  • Cesare Polito
    • 1
  • Angela La Manna
    • 1
  • Antonio Iovene
    • 1
  • Donatella Stabile
    • 1
  1. 1.Third Pediatric Clinic, Department of PediatricsSecond University of NaplesNaplesItaly

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