Effect of gonadotropins, thyrotropin, and adrenocorticotropin on the development of 12-day chick embryonic gonads

  • M. A. Shanin
  • G. Csaba
  • O. Dobozy
Rapid Communication

Summary

Gonadotropins (FSH+LH) and thyrotropin (TSH) stimulated the development of 12-day embryonic gonads, whereas adrenocorticotropin (ACTH) did not show any significant effect. It is concluded that the gonads of 12-day chick embryos have the capacity to respond to both gonadotropic and thyrotropic stimulation. This suggests that at the time when the hypothalamo-pituitary-thyroid axis begins to develop, the capacity of gonadal receptors to distinguish between gonadotropins and thyrotropin has not been established.

Key words

Gonadotropins Thyrotropin Adrenocorticotropin Chick embryo Gonad-development 

References

  1. Amir SM, Sullivan RC, Ingbar SH (1978) Binding of bovine thyrotropin to receptor in rat testis and its interaction with gonadotropins. Endocrinology 103:101–111PubMedGoogle Scholar
  2. Azukizawa M, Kurtzman G, Pekary AE, Hershman JK (1977) Comparison of the binding characteristics of bovine thyrotropin and human chorionic gonadotropin to thyroid plasma membranes. Endocrinology 101:1880–1889PubMedGoogle Scholar
  3. Csaba G, Dobozy O, Kaizer G (1979) Study of FSH-TSH functional overlap by cockerel testicle test. Horm Metab Res 11:689–692PubMedGoogle Scholar
  4. Csaba G, Shahin MA, Dobozy O (1980 in press) The overlapping effect of gonadotropins and TSH on embryonic chicken gonads. Arch Anat Histol EmbryolGoogle Scholar
  5. Csaba G (1980) Phylogeny and ontogeny of hormone receptors the selection theory of receptor formation and hormonal imprinting. Biol Rev Biol Proc Cambridge 55:47–63Google Scholar
  6. Csaba G, Shahin MA, Dobozy O (1980) Effect of combined gonadotropin-thyrotropin treatment on development of testicle and ovary in chickens. Acta Physiol Acad Sci Hung 55:163–168PubMedGoogle Scholar
  7. Davies TF, Smith BR, Rall R (1978) Binding of thyroid stimulators to guinea pig testis and thyroid. Endocrinology 103:6–10PubMedGoogle Scholar
  8. Dobozy O, Csaba G, Shahin MA, Lazáry G (1980) Histological analysis of the overlapping effect of hypophyseal hormones on the cockerel testicle. Acta Morphol Acad Sci Hung 28:11–20PubMedGoogle Scholar
  9. Fritz B, Louis BG, Tung PS, Dorrington J (1978) Action of hormones on Sertoli cells during maturation. Ann Biol Anim Biochim Biophys 18:555–563Google Scholar
  10. Huckings C (1972) Spermatogonial stem cell behavior in rodents. In: Velardo TT, Kasprow BA (eds) Proc. 3rd Pan American Congress of Anatomy, pp 395–421Google Scholar
  11. Mess B, Straznicky K (1970) Differentiation and function of the hypophyseal target organ system in chicken embryos. Publishing House of the Hungarian Academy of Science, BudapestGoogle Scholar
  12. Orth T, Christensen AK (1978) Autoradiographic localization of specifically bound125I-labeled follicle-stimulating hormone on spermatogonia of the rat testis. Endocrinology 103:1944–1951PubMedGoogle Scholar
  13. Pierce JG, Faith MR, Giudice LC, Reeve JK (1976) Structure and structure-function relationship in glycoprotein hormones in Polypeptide hormones, molecular, and cellular aspects. Elsevier, Amsterdam Ciba Found Symp 41Google Scholar
  14. Shahin MA, Csaba G, Dobozy O (1980a) Histological analysis of the effects of gonadotropins (FSH+LH) and thyrotropin (TSH) on the testes and ovaries of newly hatched chickens. Acta Morphol Acad Sci Hung 28:333–344Google Scholar
  15. Shahin MA, Csaba G, Dobozy O (1980b in press) Effects of mammalian hypophyseal hormones (gonadotropins, thyrotropin, and adrenocorticoropin) on the embryonic development of 8-days chick embryo gonads. Arch Anat Histol EmbryolGoogle Scholar
  16. Woods JE, Podczaski ES, Erton LH, Rutherford JE, McCarter CF (1977) Establishment of the adenohypophyseal-testicular axis in the chick embryo. Gen Comp Endocrinol 32:390–394PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • M. A. Shanin
    • 1
  • G. Csaba
    • 1
  • O. Dobozy
    • 1
  1. 1.Department of BiologySemmelweis University of MedicineBudapestHungary

Personalised recommendations