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Low-renin hypertension of childhood

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Abstract

Measurement of plasma renin activity (PRA) and aldosterone with a knowledge of dietary sodium balance is critical to the diagnostic evaluation of childhood hypertension. Disturbances of steroid production, regulation, metabolism and sensitivity have been implicated in the pathogenesis of low-renin hypertension in childhood. Prompt initiation of treatment is essential because the hemodynamic changes caused by long-standing hypertension may become irreversible. The clinical features and hormonal findings of the most important adrenocortical disorders associated with low-renin hypertension in childhood are summarized.

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  1. Department of Pediatrics, Division of Pediatric Endocrinology, The New York Hospital-Cornell Medical Center, 525 East 68th Street, 10021, New York, NY, USA

    Joan DiMartino-Nardi & Maria I. New

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  1. Joan DiMartino-Nardi
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  2. Maria I. New
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DiMartino-Nardi, J., New, M.I. Low-renin hypertension of childhood. Pediatr Nephrol 1, 99–108 (1987). https://doi.org/10.1007/BF00866890

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