Abstract
A white girl with a history of atypical hemolyticuremic syndrome (HUS) and persistent microangiopathic anemia, and thrombocytopenia for 2 months after the initial presentation at age 7 months, received her first cadaveric renal transplant at age 3 years. During the first 2.5 days post transplant, she developed progressive thrombocytopenia and anemia followed by tonic-clonic seizures and loss of consciousness, secondary to a diffuse cerebral infarction of the left hemisphere. Renal histology showed evidence of glomerular microthrombi and microangiopathy. A large cerebral infarct, previously described in patients during their initial presentation with HUS, presented in our patient as part of the recurrence of the disease post renal transplantation.
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Mochon, M., Kaiser, B.A., de Chadarevian, J.P. et al. Cerebral infarct with recurrence of hemolytic-uremic syndrome in a child following renal transplantation. Pediatr Nephrol 6, 550–552 (1992). https://doi.org/10.1007/BF00866501
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DOI: https://doi.org/10.1007/BF00866501