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Does kL/PCr estimate GFR, or does GFR determine k?

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References

  1. Hellerstein S, Alon U, Warady BA (1992) Creatinine for estimation of glomerular filtration rate. Pediatr Nephrol

  2. Schwartz GJ, Haycock GB, Edelmann CM Jr, Spitzer A (1976) A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 58: 259–263

    Google Scholar 

  3. Schwartz GJ, Brion LP, Spitzer A (1987) The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin North Am 34: 571–590

    Google Scholar 

  4. Schwartz GJ, Gauthier B (1985) A simple estimate for glomerular filtration rate in adolescent boys. J Pediatr 106: 522–526

    Google Scholar 

  5. Haycock GB (1989) Creatinine, body size and renal function. Pediatr Nephrol 3: 22–24

    Google Scholar 

  6. Smith HW (1951) The kidney. Structure and function in health and disease. Oxford University Press, New York, pp 231–238 520–574

    Google Scholar 

  7. Heinemann HO, Nash MA, Edelmann CM Jr (1974) Renal function test: man. In: Biology data book, vol 3, 2nd edn. Federation of American Societies for Experimental Biology and Medicine, Bethesda, pp 1992–1999

    Google Scholar 

  8. Bauer JH, Brooks CS, Burch RN (1982) Clinical appraisal of creatinine clearance as a measurement of glomerular filtration rate. Am J Kidney Dis 2: 30–35

    Google Scholar 

  9. Schuster V (1992) Renal clearance. In: Seldin DW, Giebisch G (eds) The kidney: physiology and pathophysiology. Raven Press, New York, pp 943–978

    Google Scholar 

  10. Duarte CG, Elveback LR, Liedtke RR (1980) Creatinine. In: Duarte CG (ed) Clinical laboratory procedures and diagnosis. Little Brown, Boston, pp 1–28

    Google Scholar 

  11. Schwartz GJ, Feld LG, Langford DJ (1984) A simple estimate of glomerular filtration rate in full-term infants during the first year of life. J Pediatr 104: 849–854

    Google Scholar 

  12. Haycock GB, Schwartz GJ, Wisotsky DH (1978) Geometric method for measuring body surface area: a height-weight formula validated in infants, children, and adults. J Pediatr 93: 62–66

    Google Scholar 

  13. Crawford B (1948) Depression of the exogenous creatinine/inulin or thiosulfate clearance ratios in man by Diodrast andp-aminohippuric acid. J Clin Invest 27: 171–175

    Google Scholar 

  14. Arant BS, Edelmann CM Jr, Spitzer A (1972) The congruence of creatinine and inulin clearances in children: use of the Technicon AutoAnalyzer. J Pediatr 81: 559–561

    Google Scholar 

  15. Miller BF, Winkler AW (1938) The renal excretion of endogenous creatinine in man. Comparison with exogenous creatinine and inulin. J Clin Invest 17: 31–40

    Google Scholar 

  16. Silkans GI, Jeck D, Earon J, Edelmann CM Jr, Chervu LR, Blaufox MD, Spitzer A (1973) Simultaneous measurement of glomerular filtration rate and renal plasma flow using plasma disappearance curves. J Pediatr 83: 749–757

    Google Scholar 

  17. Graystone JE (1968) Creatinine excretion during growth. In: Cheek DB (ed) Human growth. Lea and Febiger, Philadelphia, pp 182–197

    Google Scholar 

  18. Novak LP (1963) Age and sex differences in body density and creatinine excretion of high school children. Ann NY Acad Sci 110: 545–577

    Google Scholar 

  19. Brion LP, Fleischman AR, McCarton C, Schwartz GJ (1986) A simple estimate of glomerular filtration rate in low birth weight infants during the first year of life: noninvasive assessment of body composition and growth. J Pediatr 109: 698–707

    Google Scholar 

  20. Brion LP, Boeck MA, Gauthier B, Nussbaum MP, Schwartz GJ (1989) Estimation of glomerular filtration rate in anorectic adolescents. Pediatr Nephrol 3: 16–21

    Google Scholar 

  21. Forbes GB, Kreipe RE, Lipinski BA, Hodgman CH (1984) Body composition changes during recovery from anorexia nervosa: comparison of two dietary regimens. Am J Clin Nutr 40: 1137–1145

    Google Scholar 

  22. Schwartz GJ, Haycock GB, Spitzer A (1976) Plasma creatinine and urea concentration in children: normal values for age and sex. J Pediatr 88: 828–830

    Google Scholar 

  23. Feld LG, Langford DJ, Schwartz GJ (1984) The effect of neonatal hyperbilirubinemia on the measurement of plasma creatinine. Clin Pediatr (Phila) 23: 154–156

    Google Scholar 

  24. Clermont MJ, Brion L, Schwartz GJ (1986) Reliability of plasma creatinine measurement in children. Clin Pediatr (Phila) 25: 569–572

    Google Scholar 

  25. Guignard JP, Torrado A, Feldman H, Gautier E (1980) Assessment of glomerular filtration rate in children. Helv Paediatr Acta 35: 437–447

    Google Scholar 

  26. Coulthard MG, Hey EN, Ruddock V (1985) Creatinine and urea clearances compared to inulin clearance in preterm and mature babies. Early Hum Dev 11: 11–19

    Google Scholar 

  27. Aperia A, Broberger O, Elinder G, Herin P, Zetterstrom P (1981) Postnatal development of renal function in pre-term and full-term infants. Acta Paediatr Scand 70: 183–187

    Google Scholar 

  28. Counahan R, Chantler C, Ghazali S, Kirkwood B, Rose F, Barratt TM (1976) Estimation of glomerular filtration rate from plasma creatinine concentration in children. Arch Dis Child 51: 875–878

    Google Scholar 

  29. Siersbaek-Nielsen K, Hansen JM, Kampmann J, Kristensen M (1971) Rapid evaluation of creatinine clearance. Lancet 1: 1133–1134

    Google Scholar 

  30. Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16: 31–41

    Google Scholar 

  31. July DR (1979) Serum creatinine concentration in children: normal values for sex and age. N Z Med J 90: 453–456

    Google Scholar 

  32. Kuhlback B, Pasternack A, Launiala K, Stenberg M (1968) Serum creatine and creatinine in children and adolescents. Scand J Clin Lab Invest 22: 37–40

    Google Scholar 

  33. Kwong MBL, Tong TK, Mickell JJ, Chan JCM (1985) Lack of evidence that formula-derived creatinine clearance approximates glomerular filtration rate in pediatric intensive care population. Clin Nephrol 24: 285–288

    Google Scholar 

  34. Murray RL (1984) Creatinine. In: Kaplan LA, Pesce AJ (eds) Clinical chemistry. Theory, analysis and correlation. Mosby, St. Louis, pp 1248–1253

    Google Scholar 

  35. Kroll MH, Nealon L, Vogel MA, Elin RJ (1985) How certain drugs interfere negatively with the Jaffe reaction for creatinine. Clin Chem 31: 306–308

    Google Scholar 

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Schwartz, G.J. Does kL/PCr estimate GFR, or does GFR determine k?. Pediatr Nephrol 6, 512–515 (1992). https://doi.org/10.1007/BF00866487

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  • DOI: https://doi.org/10.1007/BF00866487

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