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IgG and IgA classes of anti-neutrophil cytoplasmic autoantibodies in a 13-year-old girl with recurrent Henoch-Schonlein purpura

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Abstract

We describe a 13-year-old girl with recurrent Henoch-Schonlein purpura whose symptoms were precipitated by upper respiratory tract infections. Her serum was positive for both IgG and IgA classes of anti-neutrophil cytoplasmic autoantibodies by immunofluorescence. The titers of both autoantibodies correlated with disease activity. The immunopathology underlying these findings is discussed.

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Authors and Affiliations

  1. Department of Pediatrics, Division of Pediatric Nephrology, HSC, T-II, Room 20, State University of New York at Stony Brook, 11794, Stony Brook, NY, USA

    Jen-Jar Lin, Charles L. Stewart, Frederick J. Kaskel & Richard N. Fine

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  1. Jen-Jar Lin
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  2. Charles L. Stewart
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  3. Frederick J. Kaskel
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  4. Richard N. Fine
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Lin, JJ., Stewart, C.L., Kaskel, F.J. et al. IgG and IgA classes of anti-neutrophil cytoplasmic autoantibodies in a 13-year-old girl with recurrent Henoch-Schonlein purpura. Pediatr Nephrol 7, 143–146 (1993). https://doi.org/10.1007/BF00864379

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  • DOI: https://doi.org/10.1007/BF00864379

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