Synthesis of novel functionalized 1,2,4-thiadiazoles from 3,4-diaminofurazane and isothiocyanates
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The addition of isothiocyanates to borylated 3,4-diaminofurazane is accompanied by a rearrangement to form compounds of the 1,2,4-thiadiazole series. The derivatives of 3-(5-amino-1,2,4-thiadiazole)carboxamidoxime were prepared and it was suggested to use these reagents in heterocyclic syntheses with 1,2,4-oxadiazole or a second 1,2,4-thiadiazole ring closure.
Keywordsthiadiazoles furazanes borylation isothiocyanates
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- 1.V. A. Dorokhov, E. A. Shagova, T. S. Novikova, A. B. Sheremetev, and L. I. Khmel'nitskii, Izv. Akad. Nauk, Ser. Khim., No. 10, 2363 (1988).Google Scholar
- 2.N. Vivona, G. Cusmano, and G. Macaluso, J. Chem. Soc. Perkin Trans. 1, No. 14, 1616 (1977).Google Scholar
- 3.G. Macaluso, G. Cusmano, S. Busceni, V. Frenna, N. Vivona, and N. Ruccia, Heterocycles,24, No. 12, 3433 (1986).Google Scholar
- 4.R. H. Cragg, M. F. Lappert, and B. P. Tilley, J. Chem. Soc., No. 6, pp. 2108 (1964); H. Beyer, J. W. Dawson, H. Jenne, and K. Niedenzu, J. Chem. Soc., No. 6, 2115 (1964); R. Jefferson, M. F. Lappert, P. Prokai, and B. P. Tilley, J. Chem. Soc., No. 11, 1584 (1966); V. A. Dorokhov, L. I. Lavrinovich, and B. M. Mikhailov, Dokl. Akad. Nauk,245, No. 11, 121 (1979); V. A. Dorokhov and É. A. Shagova, Izv. Akad. Nauk, Ser. Khim., No. 1, 234 (1986).Google Scholar
- 5.V. A. Dorokhov, M. N. Bochkareva, and B. M. Mikhailov, Izv. Akad. Nauk, Ser. Khim., No. 11, 2567 (1985).Google Scholar
- 6.G. E. Morris and R. Freeman, J. Am. Chem. Soc.,101, No. 3, 760 (1979).Google Scholar