Wilhelm Roux's archives of developmental biology

, Volume 190, Issue 6, pp 305–307 | Cite as

Modulatory action of 12-O-tetradecanoylphorbol-13-acetate on bud production inHydra

  • Yoshiki Shiba


A low concentration of 12-O-tetradecanoylphorbol-13-acetate (TPA, 1.0 ng/ml) induced a transient inhibition of bud production in hydra which were fed daily. However, when hydra were starved following TPA-treatment, they produced further buds. Phorbol (1.0 ng/ml) and dimethyl sulfoxide (0.001%) did not influence bud production under either feeding or starvation conditions. These results indicate that TPA modulates asexual reproduction in hydra.

Key words

Hydra Budding Tumor promoter Phorbol 


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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • Yoshiki Shiba
    • 1
  1. 1.Department of PhysiologyHiroshima University School of DentistryHiroshimaJapan

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