Abstract
A 2-year-old child underwent renal tranplantation in the presence of a post-viral enteropathy rendering him dependent on total parenteral nutrition. As part of his immunosuppression, he was given a new oral formulation of cyclosporin A (Neoral), which he was able to absorb satisfactorily, using conventional doses, during the 6 weeks he was dependent on intravenous nutrition and in the face of intermittent severe diarrhoea. An unusual pharmacokinetic profile was observed.
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References
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Jewkes, F.E.M., Jenkins, H.R., Lord, R. et al. Absorption of a new oral formulation of cyclosporin A in a child on parenteral nutrition. Pediatr Nephrol 9, 617–618 (1995). https://doi.org/10.1007/BF00860956
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DOI: https://doi.org/10.1007/BF00860956