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Anti-neutrophil cytoplasmic antibody associated glomerulonephritis in a patient with Down's syndrome

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Abstract

A 9-year-old boy with Down's syndrome developed a glomerulonephritis associated with crescents and anti-neutrophil cytoplasmic antibodies (ANCA). The patient also had type 1 diabetes mellitus, chronic lymphocytic thyroiditis, and bronchial asthma. Prednisone therapy resulted in an improvement in renal function and a reduction in ANCA titers.

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Authors and Affiliations

  1. Division of Pediatric Nephrology, The Children's Hospital, Greenville Hospital System, 890 W. Faris Road, Suite 250, Box no. 1, Greenville, South Carolina, USA

    Wm. Lane M. Robson

  2. Department of Pediatrics, University of South Carolina School of Medicine, USA

    Wm. Lane M. Robson

  3. Department of Pediatrics, The University of Calgary, The Alberta Children's Hospital, Calgary, Alberta, Canada

    Alexander K. C. Leung & Cynthia L. Trevenen

  4. Department of Pathology, The University of Calgary, The Alberta Children's Hospital, Calgary, Alberta, Canada

    Cynthia L. Trevenen

  5. Department of Internal Medicine, The Foothills Provincial Hospital, Calgary, Alberta, Canada

    Richard C. Woodman

Authors
  1. Wm. Lane M. Robson
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  2. Alexander K. C. Leung
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  3. Richard C. Woodman
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  4. Cynthia L. Trevenen
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Robson, W.L.M., Leung, A.K.C., Woodman, R.C. et al. Anti-neutrophil cytoplasmic antibody associated glomerulonephritis in a patient with Down's syndrome. Pediatr Nephrol 9, 204–205 (1995). https://doi.org/10.1007/BF00860750

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  • DOI: https://doi.org/10.1007/BF00860750

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