Pediatric Nephrology

, Volume 9, Issue 1, pp 61–73 | Cite as

Renal transplantation and chronic dialysis in children and adolescents: the 1993 annual report of the North American Pediatric Renal Transplant Cooperative Study

  • Ellis D. Avner
  • Blanche Chavers
  • E. Kenneth Sullivan
  • Amir Tejani
Original Article

Abstract

The 1993 North American Pediatric Renal Transplant Cooperative Study annual report summarizes data voluntarily contributed by 82 participating centers on 3,223 pediatric patients who received 2,819 renal transplants from January 1987 through January 1993 and 999 independent courses of dialysis from January 1992 through January 1993. In addition to updating information regarding trends and outcomes in pediatric renal transplantation presented in previous annual reports, 1st-year registry data are presented regarding current practices and trends in chronic dialysis therapy for children and adolescents in North America. Living donor graft (LDG) survival rate was 90% at 1 years 85% at 2 years and 75% at 5 years post transplant. Cadaver graft (CG) survival rates were 76%, 71% and 62% at 1, 2 and 5 years post transplant, respectively. Overall mortality post transplantation continues to be low (CG 6.8%, LDG 4%), mortality remains high in young infants. The dialysis cohort was generally younger than the transplantation cohort. In all age groups, peritoneal dialysis was utilized in the majority of pediatric patients and the overall incidence of peritonitis was 1 episode per 8.2 patient months. External percutaneous catheters were utilized as the predominant chronic hemodialysis access in the study, and access site infections ranged from 6.9% at 1 month to 13.5% at 6 months.

Key words

End-stage renal disease Renal transplantation Dialysis Graft survival Patient survival 

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Copyright information

© IPNA 1995

Authors and Affiliations

  • Ellis D. Avner
    • 1
    • 2
  • Blanche Chavers
    • 3
  • E. Kenneth Sullivan
    • 4
  • Amir Tejani
    • 5
  1. 1.Children's Hospital and Medical CenterSeattleUSA
  2. 2.University of WashingtonSeattleUSA
  3. 3.University of MinnesotaMinneapolisUSA
  4. 4.The EMMES CorporationPotomacUSA
  5. 5.NAPRTCS Clinical CoordinatingSUNY Health Ccience Center at BrooklynBrooklynUSA

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