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The application of molecular biology to the prenatal diagnosis of renal disease

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Abstract

The rapid development of new techniques in molecular biology is leading to identification of the genes responsible for a wide variety of diseases. Several renal conditions are caused by gene defects and are amenable to this approach. The process of gene mapping is discussed and the current position regarding prenatal diagnosis and carrier testing for genetic renal disease is reviewed.

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Authors and Affiliations

  1. Paediatric Research Unit, United Medical and Dental Schools of Guy's and St Thomas' Hospitals, Guy's Hospital, London Bridge, SE1 9RT, London, UK

    Frances A. Flinter & Martin Bobrow

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  1. Frances A. Flinter
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  2. Martin Bobrow
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Flinter, F.A., Bobrow, M. The application of molecular biology to the prenatal diagnosis of renal disease. Pediatr Nephrol 2, 343–350 (1988). https://doi.org/10.1007/BF00858691

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  • DOI: https://doi.org/10.1007/BF00858691

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