Abstract
Forty-nine patients with a diagnosis of idiopathic haemolytic uraemic syndrome (HUS) were investigated to determine evidence of infection by verotoxin-producingEscherichia coli (VTEC). Free faecal cytotoxin active on Vero cells (VT) was detected in 15 out of 49 patients (31%). Seroconversion or high titres of VT-neutralizing antibodies were detected in 11 out of 18 patients (61%). The results of the present study suggest an association between HUS and infection by VTEC.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Gianantonio C, Vitacco M, Mendilaharzu F, Rutty A, Mendilaharzu J (1964) The hemolytic uremic syndrome. J Pediatr 64:478–491
Voyer LE, Walther JC (1966) Contribución al conocimiento del Síndrome Urémico Hemolítico en Pediatría. Arch Argent Pediatr 64:121–130
Karmali MA, Steele BT, Petric M, Lim C (1983) Sporadic cases of haemolytic uremic syndrome associated with fecal cytotoxin and cytotoxin producing.E. coli in stools. Lancet I:619–620
Karmali MA, Petric M, Lim C, Fleming PC, Arbus GS, Lior H (1985) The association between idiopathic hemolytic uremic syndrome and infection by Verotoxin producing Escherichia coli. J Infect Dis 151:775–782
Cremer NE, Riggs JL (1979) Immunoglobulin classes and viral diagnosis. In: Lennette EH, Smith NJ (eds) Diagnostic procedures for viral rickettsial and chlamydial infections. American Public Health Association, Washington D. C.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Novillo, A.A., Voyer, L.E., Cravioto, R. et al. Haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies. Pediatr Nephrol 2, 288–290 (1988). https://doi.org/10.1007/BF00858679
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00858679