Synthesis of 2-ethynyl- and 4,5-diethynyl-1-methylimidazoles
- 53 Downloads
One, two, or three 3-methyl-3-hydroxybutynyl groups were inserted into the N-methylimidazole ring by the direct replacement of iodine, catalyzed by copper.
2-Ethynyl- and 4,5-diethynyl-1-methylimidazole were synthesized by the cleavage of the obtained imidazolylacetylenic alcohols.
KeywordsCopper Alcohol Iodine Direct Replacement
Unable to display preview. Download preview PDF.
- 1.M. S. Shvartsberg, L. N. Bizhan, and I. L. Kotlyarevskii, Izv. Akad. Nauk SSSR, Ser. Khim., 1534 (1971).Google Scholar
- 2.M. S. Shvartsberg, I. L. Kotlyarevskii, A. N. Kozhevnikova, and V. N. Andrievskii, Izv. Akad. Nauk SSSR, Ser. Khim., 1144 (1970).Google Scholar
- 3.E. E. Zaev, V. K. Voronov, M. S. Shvartsberg, S. F. Vasilevsky (Vasilevskii), Ju. N. Molin (Yu. N. Molin), and I. L. Kotljarevsky (Kotlyarevskii), Tetrahedron Lett., 617 (1968).Google Scholar
- 4.M. Haring, Helv. Chim. Acta,42, 1845 (1959).Google Scholar