Skip to main content
Log in

Protein intake can not be estimated from urinary urea excretion

  • Brief Report
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract

We assessed the relationship between protein intake (calculated from a 3-day prospective dietary diary) and 24-h urinary urea excretion in 37 children with chronic renal failure. Protein intake was not restricted during the investigation period. The 24-h urinary urea excretion correlated poorly with the protein intake estimated from the dietary diary (r=0.58). We conclude that although it is common practice to assess compliance with a protein-restricted diet in children with chronic renal failure with a dietary diary and 24-h urinary urea excretion, the value of this assessment is questionable.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Brenner BM, Meyer TW, Hostetter TH (1982) Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 307: 625–659

    PubMed  Google Scholar 

  2. Mitch WE (1985) Nutritional therapy in renal failure. In: Seldin DW, Giebisch G (eds) The kidney: physiology and pathophysiology. Raven, New York, pp 2059–2069

    Google Scholar 

  3. Blumenkrantz MJ, Kopple JD, Gutman RA, Chan YK, Barbour GL, Roberts C, Shen FH, Gandhi VC, Tucker CT, Curtis FK, Coburn JW (1980) Methods for assessing nutritional status of patients with renal failure. Am J Clin Nutr 33: 1567–1585

    PubMed  Google Scholar 

  4. Maroni BJ, Steinman TI, Mitch WE (1985) A method for estimating nitrogen intake of patients with chronic renal failure. Kidney Int 27: 58–65

    PubMed  Google Scholar 

  5. Dutch Nutrition Index (1986–1987) the Netherlands Bureau for Food and Nutrition Education. CIVO-Instituten TNO, Zeist

  6. Talke H, Schubert GE (1965) Enzymatic urea test in blood after Warburg. Klin Wochenschr 43: 174

    PubMed  Google Scholar 

  7. Ziegler EE, O'Donnell AM, Stearns G, Nelson SE, Burmeister LF, Fomon SJ (1977) Nitrogen balance studies with normal children. Am J Clin Nutr 30: 939–946

    PubMed  Google Scholar 

  8. Coles GA, Meadows JH, Bright C, Tomlinson K (1989) The estimation of dietary protein intake in chronic renal failure. Nephrol Dial Transplant 4: 877–882

    PubMed  Google Scholar 

  9. Chantler C, Holliday MA (1987) Progressive loss of renal function. In: Holliday MA, Barrat TM, Vernier RL (eds) Pediatric nephrology. Williams and Wilkins, Baltimore, pp 791–792

    Google Scholar 

  10. Kopple JD, Coburn JW (1973) Metabolic studies of low protein diets in uremia. I. Nitrogen and potassium. Medicine 52: 583–595

    PubMed  Google Scholar 

  11. Mitch W, Walser M (1977) Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids. Clin Nephrol 8: 341–344

    PubMed  Google Scholar 

  12. Diem K, Lentner C (1975) Wissenschaftliche Tabellen, 7th edn. Ciba-Geigy, Basel p 513

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kist-van Holthe tot Echten, J.E., Nauta, J., Hop, W.C.J. et al. Protein intake can not be estimated from urinary urea excretion. Pediatr Nephrol 6, 85–87 (1992). https://doi.org/10.1007/BF00856848

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00856848

Key words

Navigation