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Amino acids as CH acids

Communication 3. Kinetics of base-catalyzed exchange ofα-proton of sodium bis[n-salicylideneglycinato]cobaltate (III) and racemization of potassium (DL)-bis-[N-salicylidene (S-alaninato)]cobaltate (III)
  • Yu. N. Belokon
  • M. M. Dolgaya
  • R. L. Murtazin
  • N. I. Kuznetsova
  • V. M. Belikov
Organic and Biological Chemistry
  • 19 Downloads

Conclusions

  1. 1.

    The NMR method was used to study the lability of theα-proton in the potassium bis(N-salicyli-deneglycinato] cobaltate complex.

     
  2. 2.

    We measured the rate constants for the racemization of potassium DL-bis[N-salicylidene-(S-alaninato)] cobaltate under the influence of hydroxyl ions in water at various pH values and temperatures of the medium.

     
  3. 3.

    Potassium DL-bis[N-salicylidene-(S-alaninato)]cobaltate and potassium bis [N-salicylidenegly-cinato] cobaltate are typical CH acids, approximately corresponding to chloroform in strength.

     

Keywords

Potassium Hydroxyl Cobaltate Chloroform Cobaltate Complex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    E. E. Snell, in: Chemical and Biological Aspects of Pyridoxal Catalysis, E. E. Snell, P. M. Faselly, A. Braunstein, and A. Rossi-Fanelli (editors), Vol. 1, Pergamon Press (1963); A. E. Braunstein, Ibid., p. 579.Google Scholar
  2. 2.
    B. Pullman, in: Chemical and Biological Aspects of Pyridoxal Catalysis, Pergamon Press (1963), p. 103.Google Scholar
  3. 3.
    M. Ikawa and E. Snell, J. Am. Chem. Soc.,76, 653 (1954); K. Toi, Y. Izumi, and S. Akabori, Bull. Chem. Soc. Japan,35, 1422 (1962); K. Toi and S. Akabori, Ibid.,36, 734 (1963); K. Toi, Ibid.,36, 739 (1963); K. Hiroto and Y. Izumi, Ibid.,40, 178 (1967); K. Hiroto, K. Migomoto, and Y. Izumi, Ibid.,40, 182 (1967).Google Scholar
  4. 4.
    M. Ando and S. Emoto, Bull. Chem. Soc. Japan,42, 2624 (1969).Google Scholar
  5. 5.
    M. Ando and S. Emoto, Bull. Chem. Soc. Japan,42, 2628 (1969).Google Scholar
  6. 6.
    K. Harada and J. Oh. Hashi, J. Org. Chem.,32, 1103 (1967); T. Ichikawa, S. Maeda, Y. Araki, and Y. Ishido, J. Am. Chem. Soc.,92, 5514 (1970).Google Scholar
  7. 7.
    G. N. Weinstein, M. J. O'Connor, and R. H. Holm, Inorg. Chem.,9, 2104 (1970).Google Scholar
  8. 8.
    O. Leussing and K. S. Bai, Anal. Chem.,40, 575 (1968).Google Scholar
  9. 9.
    R. C. Burrows and J. C. Bailar, J. Am. Chem. Soc.,88, 4150 (1966).Google Scholar
  10. 10.
    E. V. Abbott and Y. E. Marvell, J. Am. Chem. Soc.,92, 5845 (1970).Google Scholar
  11. 11.
    P. K. Glasoe and F. A. Long, J. Phys. Chem.,64, 188 (1960).Google Scholar
  12. 12.
    Yu. N. Belokon, V. M. Belikov, M. M. Dolgaya, R. L. Murtazin, and N. I. Kuznetsova, Izv. Akad. Nauk SSSR, Ser. Khim., 2288 (1972).Google Scholar
  13. 13.
    D. A. Buckingham, L. G. Marzilli, and A. M. Sargeson, J. Am. Chem. Soc.,89, 5133 (1967).PubMedGoogle Scholar
  14. 14.
    D. Cram, Principles of the Chemistry of Carbanions [Russian translation], Mir (1967).Google Scholar
  15. 15.
    R. D. Gillard and D. A. Phipps, Chem. Commun., 800 (1970).Google Scholar
  16. 16.
    V. M. Belikov, Yu. N. Belokon, and N. G. Faleev, Izv. Akad. Nauk SSSR, Ser. Khim., 327 (1968).Google Scholar
  17. 17.
    J. Hine, N. W. Burski, M. Hine, and P. Bhoug, J. Am. Chem. Soc.,79, 1406 (1957).Google Scholar

Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • Yu. N. Belokon
    • 1
  • M. M. Dolgaya
    • 1
  • R. L. Murtazin
    • 1
  • N. I. Kuznetsova
    • 1
  • V. M. Belikov
    • 1
  1. 1.Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRUSSR

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