Skip to main content
SpringerLink
Log in

Amino acids as CH acids

Communication 2. C-alkylation of glycine with methyl acrylate in metal complexes of n-pyruvylideneglycine and n-salicylideneglycine

  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    A study was made of the alkylation of glycine with methyl acrylate in complexes of the transition metals of type: metal N-salicylideneglycinate. The C-alkylation of glycine is observed in Cu(II) complexes, while N-alkylation is observed in Ni(II) and Co(II) complexes.

  2. 2.

    A study was made of the C-alkylation of glycine with methyl acrylate in Cu(II) complexes and it was established that the yield of glutamic acid depends on the nature of the catalyst and the experimental conditions. The C-alkylation of glycine can also be accomplished in copper pyruvylideneglycinate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. Yu. N. Belokon, V. M. Belikov, N. I. Kuznetsova, and M. M. Dolgaya, Izv. Akad. Nauk SSSR, Ser. Khim., 1338 (1972).

  2. M. Sato, K. Okawa, and S. Akabori, Bull. Chem. Soc. Japan,30, 937 (1957).

    Google Scholar 

  3. K. Harada, J. Org. Chem.,32, 1103 (1967).

    Google Scholar 

  4. T. Ishikawa, S. Moeda, I. Araki, and I. Ishido, J. Am. Chem. Soc.,92, 5514 (1970).

    PubMed  Google Scholar 

  5. S. Nakahara, S. Nishikawa, and J. Mitani, Bull. Chem. Soc. Japan,40, 2212 (1967).

    Google Scholar 

  6. E. E. Snell, P. M. Fasella, A. Braunstein, and A. Rossi Fanelli (editors), Chemical and Biological Aspects of Pyridoxal Catalysis, Vol. 1, Pergamon Press (1963).

  7. H. H. Offenheym and P. J. Lennesheus, J. Agr. Food Chem.,18, 1070 (1970).

    Google Scholar 

  8. H. E. Zaugg and A. D. Schaefer, Anal. Chem.,36, 2121 (1964).

    Google Scholar 

  9. A. Nakahara, Bull. Chem. Soc. Japan,32, 1196 (1959).

    Google Scholar 

  10. L. Theriot, G. Carlisle, and H. Hu, J. Inorg. Nucl. Chem.,31, 2894 (1969).

    Google Scholar 

  11. A. Nakahara, H. Jamomoto, and H. Matsumoto, Bull. Chem. Soc. Japan,37, 1337 (1964).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, USSR

    Yu. N. Belokon, N. I. Kuznetsova, V. M. Belikov & R. L. Murtazin

Authors
  1. Yu. N. Belokon
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. I. Kuznetsova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. M. Belikov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. L. Murtazin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

See [1] for Communication 1.

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 10, pp. 2288–2292, October, 1972.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Belokon, Y.N., Kuznetsova, N.I., Belikov, V.M. et al. Amino acids as CH acids. Russ Chem Bull 21, 2221–2224 (1972). https://doi.org/10.1007/BF00855302

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00855302

Keywords

Search

Navigation