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Synthesis of a specific inhibitor of trypsin, containing a heavy atom

  • Organic and Biological Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    We synthesized 1-chloro-3-L-p-iodobenzenesulfonamido-7-amino-2-heptanone, which is a specific inhibitor of trypsin, and contains the heavy iodine atom. We also obtained some preparations of the inhibited enzyme.

  2. 2.

    The inhibition constant was determined.

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Authors and Affiliations

  1. Institute of Crystallography, Academy of Sciences of the USSR, USSR

    I. P. Kuranova & E. A. Smirnova

Authors
  1. I. P. Kuranova
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  2. E. A. Smirnova
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 11, pp. 2535–2540, November, 1971.

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Kuranova, I.P., Smirnova, E.A. Synthesis of a specific inhibitor of trypsin, containing a heavy atom. Russ Chem Bull 20, 2402–2406 (1971). https://doi.org/10.1007/BF00854322

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  • DOI: https://doi.org/10.1007/BF00854322

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