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Pediatric Nephrology

, Volume 2, Issue 4, pp 447–452 | Cite as

Hyperlipidemia in pediatric patients undergoing peritoneal dialysis

  • U. Querfeld
  • I. B. Salusky
  • P. Nelson
  • J. Foley
  • R. N. Fine
Original Article

Abstract

We evaluated serial measurements of serum lipid levels in 68 patients aged 12.6±4.7 years undergoing treatment with continuous ambulatory peritoneal dialysis/continuous cycling peritoneal dialysis (CAPD/CCPD). Fasting mean levels of triglycerides (TG) and cholesterol (C) were elevated above the 95th percentile of published normal values by 102% and 19%, respectively, at the start of dialysis. Except for a shortterm decrease in TG levels at 6 and 9 months, no significant change in mean lipid levels was observed during a follow-up period of 2 years. At initiation of dialysis, elevated TG and C levels were present in 90% and 69% of the patients, respectively. The prevalence of hyperlipidemia (HL) varied between 63% and 88% (TG) and 61% and 93% (C), respectively, during the follow-up period. TG and C levels were not correlated with caloric intake (evaluated in 17 patients), serum albumin levels, treatment modality (CAPD or CCPD), a history of the nephrotic syndrome, or previous treatment with hemodialysis or transplantation. However, a significant inverse correlation was observed between age and serum lipids at the initiation of dialysis treatment and after 1 year (TG:r=−0.40; C:r=−0.44). Our data indicate a high prevalence of HL but no significant change of serum lipid levels during 2 years of treatment with CAPD/CCPD.

Key words

Hyperlipidemia Triglycerides Cholesterol Peritoneal dialysis 

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Copyright information

© IPNA 1988

Authors and Affiliations

  • U. Querfeld
    • 1
  • I. B. Salusky
    • 1
  • P. Nelson
    • 1
  • J. Foley
    • 1
  • R. N. Fine
    • 1
  1. 1.Department of PediatricsUCLA School of Medicine, Division of Pediatric NephrologyLos AngelesUSA

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