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Reaction of epoxybutyraldehyde diethyl acetal with ammonia and benzylamine

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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

The opening of the oxide ring of the diethyl acetal of epoxybutyraldehyde by ammonia or benzylamine goes selectively both structurally and sterically, with the formation of o-hydroxy-β-amino compounds of the erythro series.

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Literature cited

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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 919–920, May, 1966.

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Kozyrkin, B.I., Yanovskaya, L.A. & Kucherov, V.F. Reaction of epoxybutyraldehyde diethyl acetal with ammonia and benzylamine. Russ Chem Bull 15, 876–877 (1966). https://doi.org/10.1007/BF00849391

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  • DOI: https://doi.org/10.1007/BF00849391

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