Skip to main content
Log in

Aggressive therapy of infants with renal failure

  • Original Article
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract

Nine infants, who presented with renal failure within the first 3 months of life, were treated with continuous ambulatory peritoneal dialysis (CAPD). Seven infants survived to an age of 12–15 months, when they received transplants. Two patients died while on CAPD. Six infants are alive with a functioning renal allograft, at an average age of 35.5 months and an average of 22 months post-transplant. Neurological development is normal in four of the six infants tested. The mean current height of the six transplant recipients is just below 2 SD from the mean.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Betts PR, McGrath G (1972) Growth pattern and dietary intake in children with chronic renal insufficiency. Br Med J 2:189–194

    Google Scholar 

  2. Kleinknecht C, Broyer M, Gagnadoux M, Martihenneberg C, Dartois AM, Kermanach C, Pouliquen M, Degoulet D, Usberti M, Roy MP (1980) Growth in children treated with long term dialysis. A study of 76 patients. Adv Nephrol 9:133–163

    Google Scholar 

  3. Broyer M, Kleinknecht C, Loirat C, Martihenneberg C, Roy MT (1974) Growth in children with long term hemodialysis. J Pediatr 84:642–649

    PubMed  Google Scholar 

  4. Chantler C, Carter JE, Bewick M, Counahan R, Cameron JS, Ogg CS, Williams DA, Winder E (1980) Ten years experience with hemodialysis in renal transplant. Arch Dis Child 55:435–445

    PubMed  Google Scholar 

  5. Baluarte JH, Gruskin AB, Hiner LB, Foley CM, Grover WD (1977) Encephalopathy in children with chronic renal failure. Proc Dial Transplant Forum 7:95–97

    Google Scholar 

  6. Trompeter RS, Polinsky MS, Andreoli SA, Fennell RS (1986) Neurological complications of renal failure. Am J Kidney Dis 4:318–323

    Google Scholar 

  7. Rotundo A, Nevins TE, Lipton M, Lockman LA, Mauer SM, Michael AF (1982) Progressive encephalopathy in children with chronic renal insufficiency in infancy. Kidney Int 21:486–491

    PubMed  Google Scholar 

  8. Andreoti SP, Bergstein JM, Sheppard DJ (1984) Aluminum intoxication from aluminum containing phosphate binders in children with azotemia not undergoing dialysis. N Engl J Med 310:1079–1084

    PubMed  Google Scholar 

  9. Alexander SR (1984) Treatment of infants with ESRD. In: Fine RN, Gruskin AB (eds) End stage renal disease in children. W. B. Saunders, Philadelphia, p 17

    Google Scholar 

  10. Mauer SM, Lynch RE (1976) Hemodialysis techniques for infants and children. Pediatr Clin North Am 23:843–856

    PubMed  Google Scholar 

  11. Popovich RP, Moncrief JW, Nolph KD, Ghods AJ, Twardowski ZJ, Pyle WK (1978) Continuous ambulatory peritoneal dialysis. Ann Intern Med 88:449–456

    PubMed  Google Scholar 

  12. Alexander SR, Tseng CH, Maksym KA, Talwalkar YB (1980) Early clinical experience with continuous ambulatory peritoneal dialysis (CAPD) in infants and children. Clin Res 128:131A

    Google Scholar 

  13. Kohaut EC (1983) Growth in children treated with continuous ambulatory peritoneal dialysis. Int J Pediatr Nephrol 4:93–98

    PubMed  Google Scholar 

  14. Balfe JW, Vigneux A, Willumsen J, Hardy BE (1981) The use of CAPD in the treatment of children with end stage renal disease. Perit Dial Bull 1:35–38

    Google Scholar 

  15. Baum M, Powell D, Calvin S, McDaid T, McHenry K, Mar H, Potter D (1982) Continuous ambulatory peritoneal dialysis in children. N Engl J Med 307:1537–1541

    Google Scholar 

  16. Conley SB, Brewer ED, Grady S, Wilson D (1982) Normal growth in very small children on peritoneal dialysis. Program and abstracts. National Kidney Foundation, Chicago, p 8

    Google Scholar 

  17. Brewer ED, Holmes S, Tealey J (1985) Initiation and maintenance of growth in infants with ESRD managed with CAPD and nasogastric feeding. Abstracts American Society of Nephrology, New York, p 81A

    Google Scholar 

  18. Alexander SR, Tank ES (1982) Surgical aspects of continuous ambulatory peritoneal dialysis in infants, children and adolescents. J Urol 127:501–504

    PubMed  Google Scholar 

  19. Orkin BA, Fonkalsrud EW, Salusky IB, Ettinger RB, Hall T, Jordan SC, Fine RN (1983) Continuous ambulatory peritoneal dialysis catheters in children. Arch Surg 118: 1398–1402

    PubMed  Google Scholar 

  20. Kohaut EC, Balfe JW, Potter D, Alexander SR, Lum G (1983) Hypermagnesemia and mild hypocarbia in pediatric patients on continuous ambulatory peritoneal dialysis. Perit Dial Bull 3:42

    Google Scholar 

  21. Kohaut EC (1986) The effect of dialysate volume on ultrafiltration in young patients. Int J Pediatr Nephrol 7: 13–16

    PubMed  Google Scholar 

  22. Southwest Pediatric Nephrology Study Group (1985) Continuous ambulatory and continuous cycling peritoneal dialysis in children. Kidney Int 27:558–564

    Google Scholar 

  23. Kohaut EC (1983) Growth in children treated with continuous ambulatory peritoneal dialysis. Int J Pediatr Nephrol 4:93–98

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kohaut, E.C., Whelchel, J., Waldo, F.B. et al. Aggressive therapy of infants with renal failure. Pediatr Nephrol 1, 150–153 (1987). https://doi.org/10.1007/BF00849286

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00849286

Key words

Navigation