Synthesis of some derivatives of α-phenylethyl- and α-phenylisopropylboronic acids
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The synthesis of theα-phenylethyl- andα-phenylisopropylmagnesium chlorides in THF at 0 to − 10° was described. Whenα-phenylisopropylmagnesium chloride is synthesized in THF at 20–45° it reacts with the THF to yield 5-methyl-5-phenyl-1-hexanol.
When reacted with methyl borate, theα-phenylethyl- andα-phenylisopropylmagnesium chlorides give theα-phenylethyl- andα-phenylisopropylboronic acids. We also prepared the anhydride ofα-phenylethylboronic acid and the diethanolamine esters ofα-phenylethyl- andα-phenylisopropylboronic acid.α-Phenylethylmercury chloride was obtained from the and mercuric chloride.
KeywordsMethyl Chloride Ester Anhydride Borate
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