Synthesis of some derivatives of α-phenylethyl- and α-phenylisopropylboronic acids

  • N. V. Kruglova
  • R. Kh. Freidlina
Brief Communications


  1. 1.

    The synthesis of theα-phenylethyl- andα-phenylisopropylmagnesium chlorides in THF at 0 to − 10° was described. Whenα-phenylisopropylmagnesium chloride is synthesized in THF at 20–45° it reacts with the THF to yield 5-methyl-5-phenyl-1-hexanol.

  2. 2.

    When reacted with methyl borate, theα-phenylethyl- andα-phenylisopropylmagnesium chlorides give theα-phenylethyl- andα-phenylisopropylboronic acids. We also prepared the anhydride ofα-phenylethylboronic acid and the diethanolamine esters ofα-phenylethyl- andα-phenylisopropylboronic acid.α-Phenylethylmercury chloride was obtained from the and mercuric chloride.



Methyl Chloride Ester Anhydride Borate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    N. V. Kruglova and R. Kh. Freidlina, Izv. AN SSSR, Ser. khim.,1965, 2044.Google Scholar
  2. 2.
    D. S. Matteson and R. A. Bowie, J. Amer. Chem. Soc.,87, 2587 (1965).Google Scholar
  3. 3.
    H. L. Cohen and G. F. Wright, J. Organ. Chem.,18, 432 (1953).Google Scholar
  4. 4.
    I. Elphimoff-Felkin and H. Felkin, Bull. soc. chim. France,1957, 450.Google Scholar
  5. 5.
    I. I. Lapkin and A. V. Lyubimova, Zh. obshch. khim.,18, 701 (1948).Google Scholar
  6. 6.
    S. T. Ioffe and A. N. Nesmeyanov, “Methods of Heteroorganic Chemistry” [in Russian], Chapter 1, “Nauka,” Moscow-Leningrad (1963).Google Scholar
  7. 7.
    Kenji Kaji and Hiromu Magashima, Chem. Abstrs.,51, 4309 (1957).Google Scholar
  8. 8.
    R. R. Dreisbach and R. A. Martin, Industr. and Engng. Chem.,41, 2875 (1949).Google Scholar

Copyright information

© Consultants Bureau 1967

Authors and Affiliations

  • N. V. Kruglova
    • 1
  • R. Kh. Freidlina
    • 1
  1. 1.Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRUSSR

Personalised recommendations