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Neural induction in amphibians

Transmission of a neuralizing factor
  • Manorama John
  • Jutta Janeczek
  • Jochen Born
  • Peter Hoppe
  • Heinz Tiedemann
  • Hildegard Tiedemann
Rapid Communications

Summary

The neural plates of very early neurula stages of Triturus alpestris were removed, the material which is released from the extracellular space between mesoderm and neural plate to the medium in which the embryos were dissected was isolated and extracted with phenol. The protein isolated from the phenol layer showed neural inducting activity. Proteoglycans isolated from the aqueous layer did not show such inducing activity. These results together with previously published experiments (Wilhelm Roux's Arch 184: 285–299) suggest that a neuralizing factor which is released from the mesoderm acts on the inner surface of the overlying dorsal ectoderm.

Key words

Neuralizing factor Transmission Mesoderm Extracellular material Triturus embryo 

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References

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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • Manorama John
    • 1
  • Jutta Janeczek
    • 1
  • Jochen Born
    • 1
  • Peter Hoppe
    • 1
  • Heinz Tiedemann
    • 1
  • Hildegard Tiedemann
    • 1
  1. 1.Institut für Molekularbiologie und BiochemieFreie Universität BerlinBerlin 33

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