Binucleate cells in mouse morulae

  • Maria Salomea Soltyńska
  • Hanna Balakier
  • Anna Witkowska
  • Jolanta Karasiewicz
Rapid Communications

Summary

Mouse morulae from two strains were examined in whole mounts after dissociation of embryos into single cells and were analysed in serial sections by light and electron microscopy. One or two binucleate cells per embryo were discovered in a statistically significant number of morulae. The frequency of morulae with binucleate cell(s) was higher in older morulae than in younger ones. Binucleate cells were always the outer cells of the embryo. Their ultrastructure did not differ from the ultrastructure of mononucleate cells. It is suggested that cell binuclearity at the morula stage is a possible way to polyploidization of nuclei, resulting in the formation of primary trophoblast giant cells.

Key words

Mouse Morula Binucleate cell Polyploidization Trophoblast 

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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Maria Salomea Soltyńska
    • 1
  • Hanna Balakier
    • 2
  • Anna Witkowska
    • 3
  • Jolanta Karasiewicz
    • 4
  1. 1.Department of Cytology, Zoological InstituteUniversity of WarsawWarszawaPoland
  2. 2.Department of ZoologyUniversity of TorontoTorontoCanada
  3. 3.Department of Histology and EmbryologyFaculty of Veterinary MedicineWarszawa
  4. 4.Department of Embryology, Zoological InstituteUniversity of WarsawWarszawaPoland

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