Mutations of early neurogenesis inDrosophila

  • Ruth Lehmann
  • Ursula Dietrich
  • F. Jiménez
  • J. A. Campos-Ortega
Rapid Communication


Embryonic lethal mutations at the Notch locus are known to produce a conspicuous central nervous system hypertrophy accompanied by a hypotrophy of the epidermal sheath. We have studied several zygotic mutants belonging to four different autosomal complementation groups which produce the same phenotype. The embryonic development of the new mutants, as well as that of Notch, consists of an initial enlargement of the neurogenic region at the expenses of epidermal cell precursors. The possibility is discussed that these five loci are involved in the determination of neural and epidermal cell precursors.

Key words

Early neurogenesis Mutants Drosophila melanogaster 


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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • Ruth Lehmann
    • 1
  • Ursula Dietrich
    • 1
  • F. Jiménez
    • 1
  • J. A. Campos-Ortega
    • 1
  1. 1.Institut für Biologie IIIFreiburg i. Br.Germany

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